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Clinical trialNCT05020860RecruitingPhase 2Interventional

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

SponsorBaylor Breast Care CenterEnrollment185Breast CancerBreast Cancer FemaleBreast Cancer InvasiveBreast Cancer Stage IIBreast Cancer Stage IIIBreast Neoplasm+5 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to learn whether clinical response (the amount a tumor shrinks based on imaging or tumor measurements obtained by physical exam) predicts pathologic response (the amount of tumor remaining when surgery is performed) in participants with breast cancer who are receiving chemotherapy prior to surgery.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Harris Health System - Smith Clinic

    Houston, Texas, United States

    Mothaffar Rimawi, MD →
    Recruiting
  • O'Quinn Medical Tower - Mcnair Campus - Dan L Duncan Comprehensive Cancer Center

    Houston, Texas, United States

    Mothaffar Rimawi, MD →
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CarboplatinCyclophosphamideDoxorubicinPaclitaxelPembrolizumabPertuzumabHyaluronidase / pertuzumab / trastuzumabTrastuzumab
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
18 Apr 2023
Primary completion
31 Aug 2027
Completion
30 Nov 2029
Last update posted
27 Feb 2025
Registered enrollment
185
Registry id
NCT05020860
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.