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Clinical trialNCT05047185CompletedPhase 2Interventional

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II

SponsorPharvaris Netherlands B.V.Enrollment34C1 Esterase Inhibitor DeficiencyC1 Inhibitor DeficiencyHereditary AngioedemaHereditary Angioedema - Type 1Hereditary Angioedema - Type 2Hereditary Angioedema Attack+4 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Emel Aygören-Pürsün, MD

    University Hospital Frankfurt - Goethe University, Frankfurt, Germany

    Principal Investigator
  • Marc Riedl, MD

    UC San Diego, La Jolla, California, United States

    Principal Investigator

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

19 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Austria
  • Study Site

    Vienna, Austria

Bulgaria
  • Study Site

    Sofia, Bulgaria

Canada
  • Study Site

    Ottawa, Ontario, Canada

  • Study Site

    Montreal, Quebec, Canada

Germany
  • Study Site

    Berlin, Germany

  • Study Site

    Frankfurt, Germany

Ireland
  • Study Site

    Dublin, Ireland

Italy
  • Study Site

    Padua, PD, Italy

  • Study Site

    Milan, Italy

  • Study Site

    Palermo, Italy

Poland
  • Study Site

    Krakow, Poland

United Kingdom
  • Study Site

    Brighton, England, United Kingdom

  • Study Site

    Bristol, England, United Kingdom

  • Study Site

    Cambridge, England, United Kingdom

  • Study Site

    London, England, United Kingdom

  • Study Site

    Southampton, England, United Kingdom

United States
  • Study Site

    Birmingham, Alabama, United States

  • Study Site

    Paradise Valley, Arizona, United States

  • Study Site

    St Louis, Missouri, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
19 Apr 2022
Primary completion
30 Jun 2025
Completion
30 Jun 2025
Last update posted
30 Jul 2025
Registered enrollment
34
Registry id
NCT05047185

Cross-registrations

EU-CTR / CTIS (EudraCT)2021-000227-13

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.