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Clinical trialNCT05077800Active, not recruitingPhase 2Interventional

FOLFIRINOX + Elraglusib + Losartan In Pancreatic Cancer

SponsorColin D. Weekes, M.D., PhDEnrollment70Pancreatic AdenocarcinomaPancreatic Adenocarcinoma Metastatic
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant to standard treatment for the disease. The names of the study drugs involved in this study are: * 9-ING-41 * Losartan * Ferumoxytol * FOLFIRINOX (made up of 4 different drugs): * 5-Fluorouracil (5-FU) * Oxaliplatin * Irinotecan * Leucovorin
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Colorado Cancer Center

    Aurora, Colorado, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, United States

  • Massachusetts General Hospital

    Charlestown, Massachusetts, United States

  • University of Washington School of Medicine

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

9-ING-41FOLFIRNINOXLosartan →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Mar 2022
Primary completion
31 Dec 2026
Completion
31 Dec 2026
Last update posted
13 Apr 2026
Registered enrollment
70
Registry id
NCT05077800
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.