Clinical trialNCT05080764CompletedPhase 2Interventional

Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in Adults

SponsorBiofrontera Inc.Enrollment120Acne Vulgaris

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The aim of this study is to test the safety and efficacy of photodynamic therapy (PDT) for the medication Ameluz® performed with the PDT-lamp BF-RhodoLED® in comparison to the respective placebo treatment for moderate to severe Acne vulgaris.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Mitchel P Goldman, MD
Dermatology Cosmetic Laser Medical Associates of La Jolla, Inc.
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

First Oc Dermatology
Fountain Valley, California, United States
Cosmetic Laser Dermatology
San Diego, California, United States
Dermatology Associates Pa of the Palm Beaches
Delray Beach, Florida, United States
Forcare Clinical Research
Tampa, Florida, United States
Delricht Research
Baton Rouge, Louisiana, United States
Skin Search of Rochester, Inc
Rochester, New York, United States
Clinical Research Center of the Carolinas
Charleston, South Carolina, United States
Dermresearch Pa
Austin, Texas, United States
Austin Institute for Clinical Research Inc.
Pflugerville, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 10 Dec 2021
Primary completion: 22 Aug 2025
Completion: 7 Jan 2026
Last update posted: 8 Jul 2026
Registered enrollment: 120
Registry id: NCT05080764

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.