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Clinical trialNCT05125471CompletedPhase 2Interventional

Cobimetinib In Extracranial Arteriovenous Malformations (COBI-AVM Study)

SponsorUniversity of ArkansasEnrollment3Arteriovenous Malformations (Extracranial)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this open-label study is to evaluate the safety and efficacy of cobimetinib in extracranial AVM.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Joana M Mack, MD

    University of Arkansas for Medical Sciences, Arkansas Children's Hospital

    Principal Investigator
    clinicaltrials.gov ↗
  • Kevin J Bielamowicz, MD,

    University of Arkansas for Medical Sciences, Arkansas Children's Hospital

    Principal Investigator
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Arkansas Children'S Hospital

    Little Rock, Arkansas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cobimetinib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
26 Jul 2022
Primary completion
3 Sept 2025
Completion
3 Sept 2025
Last update posted
10 Sept 2025
Registered enrollment
3
Registry id
NCT05125471
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.