Clinical trialNCT05168163RecruitingPhase 2Interventional

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

SponsorAcademic and Community Cancer Research UnitedEnrollment122Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+3 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Wen Wee Ma
Academic and Community Cancer Research United
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Mayo Clinic in Arizona
Scottsdale, Arizona, United States
Tanios S. Bekaii-Saab
Recruiting
Mayo Clinic in Florida
Jacksonville, Florida, United States
Withdrawn
Cleveland Clinic Weston Florida
Weston, Florida, United States
Withdrawn
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States
Chih-Yi Liao
Not, yet, recruiting
Carle Cancer Center Nci Community Oncology Research Program
Urbana, Illinois, United States
Suparna Mantha
Recruiting
University Medical Center New Orleans
New Orleans, Louisiana, United States
Jyotsna Fuloria
Recruiting
Michigan Cancer Research Consortium Ncorp
Ann Arbor, Michigan, United States
Elie G. Dib
Recruiting
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States
Oxana V. Crysler
Not, yet, recruiting
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Nguyen Tran
Recruiting
Roswell Park Cancer Institute
Buffalo, New York, United States
Renuka V. Iyer
Recruiting
Duke University Medical Center
Durham, North Carolina, United States
Completed
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States
Withdrawn
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Dulabh K. Monga
Recruiting
Rapid City Regional Hospital
Rapid City, South Dakota, United States
Abdel-Ghani Azzouqa
Recruiting
Froedtert and the Medical College of Wisconsin Laps
Milwaukee, Wisconsin, United States
Aditya Shreenivas
Recruiting
Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Aditya Shreenivas
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 27 May 2022
Primary completion: 31 Dec 2025
Completion: 31 Dec 2026
Last update posted: 16 Sept 2025
Registered enrollment: 122
Registry id: NCT05168163

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.