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Clinical trialNCT05168813CompletedPhase 2/PHASE3Interventional

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

SponsorCOVID-19 Prevention NetworkEnrollment14,237COVID-19HIV InfectionsSARS-CoV-2 Infection
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

47 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Botswana
  • Gaborone Crs

    Gaborone, Botswana

Eswatini
  • Eswatini Prevention Center Crs

    Mbabane, Hhohho Region, Eswatini

Kenya
  • Moi University Clinical Research Centre

    Eldoret, Kenya

  • Kisumu - Kombewa Crs

    Kisumu, Kenya

  • Kisumu Crs

    Kisumu, Kenya

Malawi
  • Blantyre Crs

    Blantyre, Malawi

  • Malawi Crs

    Lilongwe, Malawi

South Africa
  • Synergy Biomed Research Institute

    East London, Eastern Cape, South Africa

  • Nelson Mandela Academic Research Unit Crs

    Mthatha, Eastern Cape, South Africa

  • Phoenix Pharma (pty) Ltd

    Port Elizabeth, Eastern Cape, South Africa

  • Josha Resarch Crs

    Bloemfontein, Free State, South Africa

  • Mecru Crs

    Ga-Rankuwa, Gauteng, South Africa

  • Clinical Hiv Research Unit (chru)/ Helen Joseph Crs

    Johannesburg, Gauteng, South Africa

  • Newtown Clinical Research

    Johannesburg, Gauteng, South Africa

  • Soweto - Bara Crs

    Johannesburg, Gauteng, South Africa

  • Wits Rhi Ward 21 Crs

    Johannesburg, Gauteng, South Africa

  • Merc Kempton Park

    Pretoria, Gauteng, South Africa

  • Synexus Stanza Clinical Research Centre (crs)

    Pretoria, Gauteng, South Africa

  • Tembisa Clinic 4 Covpn Crs

    Tembisa, Gauteng, South Africa

  • Caprisa Ethekwini Crs

    Durban, KwaZulu-Natal, South Africa

  • Tongaat Crs

    Durban, KwaZulu-Natal, South Africa

  • Vulindlela Crs

    Durban, KwaZulu-Natal, South Africa

  • Isipingo Crs

    Isipingo, KwaZulu-Natal, South Africa

  • Qhakaza Mbokodo Research Clinic Crs

    Ladysmith, KwaZulu-Natal, South Africa

  • Merc Middelburg

    Middelburg, Mpumalanga, South Africa

  • Aurum Institute Klerksdorp Crs

    Klerksdorp, North West, South Africa

  • Rustenburg Crs

    Rustenburg, North West, South Africa

  • Emavundleni Crs

    Cape Town, Western Cape, South Africa

  • Fam-Cru (family Clinical Research Unit)

    Cape Town, Western Cape, South Africa

  • Groote Schuur Hiv Crs

    Cape Town, Western Cape, South Africa

  • Masiphumelele Clinical Research Site (masi) Crs

    Cape Town, Western Cape, South Africa

  • Task Central

    Cape Town, Western Cape, South Africa

  • Univeristy of Cape Town Lung Crs Institute

    Cape Town, Western Cape, South Africa

  • Task Eden

    George, Western Cape, South Africa

  • Synexus Helderberg

    Stellenbosch, Western Cape, South Africa

  • Ndlovu Research Centre Covpn Crs

    Elandsdoorn, South Africa

  • Kliptown Soweto Crs

    Johannesburg, South Africa

  • Phru Matlosana Crs

    Klerksdorp, South Africa

  • Merc Welkom

    Welkom, South Africa

Uganda
  • Uvri-Iavi Hiv Vaccine Program Ltd. Crs

    Entebbe, Uganda

7 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Dec 2021
Primary completion
19 Apr 2024
Completion
19 Apr 2024
Last update posted
21 Apr 2026
Registered enrollment
14,237
Registry id
NCT05168813

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.