Clinical trialNCT05172011Active, not recruitingObservational

Understanding the Long-term Impact of COVID on Children and Families

SponsorNYU Langone HealthEnrollment15,028SARS-CoV-2 Infection

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals age 0-25 years who will enter the cohort with and without SARS-CoV-2 infection at varying stages before and after infection. Individuals with and without SARS-CoV-2 infection and with or without PASC symptoms will be followed to identify risk factors and occurrence of PASC. This study will be conducted in the United States and participants will be recruited through inpatient, outpatient, and community-based settings. Study data including age, demographics, social determinants of health, medical history, vaccination history, details of acute SARS-CoV-2 infection, overall health and physical function, and PASC symptoms will be reported by participants or collected from the electronic health record using a case report form at specified intervals. Biologic specimens will be collected at specified intervals, with some tests performed in local clinical laboratories and others performed by centralized research centers or banked in the Biospecimen Repository. Advanced clinical examinations and radiologic examinations will be performed at local study sites with cross-site standardization.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Andrea Troxel, ScD
NYU Langone Health
Principal Investigator
clinicaltrials.gov ↗
Leora Horwitz, MD
NYU Langone Health
Principal Investigator
clinicaltrials.gov ↗
Stuart Katz, MD, MS
NYU Langone Health
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

65 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham (pregnancy Cohort)
Birmingham, Alabama, United States
Arkansas Children'S Hospital and Research Institute
Little Rock, Arkansas, United States
University of California San Diego
La Jolla, California, United States
Children'S Hospital Los Angeles
Los Angeles, California, United States
University of California San Diego Health - Rady Children'S Hospital
San Diego, California, United States
University of California San Francisco
San Francisco, California, United States
University of California San Francisco (pregnancy Cohort)
San Francisco, California, United States
Connecticut Children'S Medical Center
Hartford, Connecticut, United States
Yale School of Medicine (ysm)
New Haven, Connecticut, United States
Christianacare Health System
Newark, Delaware, United States
Nemours Children'S Health
Wilmington, Delaware, United States
George Washington University
Washington D.C., District of Columbia, United States
Kapi'Olani Medical Center for Women & Children
Honolulu, Hawaii, United States
Northwestern University
Evanston, Illinois, United States
Northshore University Healthsystem
Glenview, Illinois, United States
American Academy of Pediatrics
Itasca, Illinois, United States
American Academy of Family Physicians
Leawood, Kansas, United States
University of Louisville - Norton Children'S Hospital
Louisville, Kentucky, United States
Louisiana State University (lsu) - Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States
Tulane University
New Orleans, Louisiana, United States
Johns Hopkins University
Baltimore, Maryland, United States
Harvard Medical School
Boston, Massachusetts, United States
Harvard School of Public Health
Boston, Massachusetts, United States
Mass General Brigham - Harvard University
Boston, Massachusetts, United States
Northeastern University
Boston, Massachusetts, United States
Central Michigan University - College of Medicine
Detroit, Michigan, United States
Mayo Clinic
Rochester, Minnesota, United States
University of Nebraska Medical Center
Omaha, Nebraska, United States
Dartmouth-Hitchcock
Lebanon, New Hampshire, United States
Hackensack University Medical Center
Hackensack, New Jersey, United States
Rutgers University
New Brunswick, New Jersey, United States
Saint Peter'S University Hospital
New Brunswick, New Jersey, United States
the Pediatric Specialty Center at Saint Barnabas
West Orange, New Jersey, United States
University of New Mexico Health Sciences Center
Albuquerque, New Mexico, United States
Columbia University
New York, New York, United States
Columbia University (pregnancy)
New York, New York, United States
Nyu Langone Health
New York, New York, United States
Newyork-Presbyterian Hospital
Queens, New York, United States
New York Medical College
Valhalla, New York, United States
University of North Carolina (unc) at Chapel Hill
Chapel Hill, North Carolina, United States

25 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Mar 2022
Primary completion: 1 Apr 2027
Completion: 23 May 2027
Last update posted: 31 Dec 2025
Registered enrollment: 15,028
Registry id: NCT05172011

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.