ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- Rahul P. Sharma, MBBS
Stanford University
Principal Investigator - Tamim M. Nazif, MD
Columbia University
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
65 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- St. Andrews War Memorial Hospital
Spring Hill, Queensland, Australia
Active, not recruiting - Royal Adelaide Hospital
Adelaide, South Australia, Australia
Active, not recruiting - the Royal Melbourne Hospital
Parkville, Australia
Active, not recruiting
- St. Paul'S Hospital System
Vancouver, British Columbia, Canada
Active, not recruiting - Hamilton Health Services
Hamilton, Ontario, Canada
Active, not recruiting - Institut Universitaire de Cardiologie Et de Pneumologie de Quebec- Universite Laval
Québec, Quebec, Canada
Active, not recruiting
- Christchurch Hospital
Christchurch, New Zealand
Active, not recruiting
- Scripps Memorial Hospital la Jolla
La Jolla, California, United States
Active, not recruiting - Cedars-Sinai Medical Center
Los Angeles, California, United States
Recruiting - Kaiser Los Angeles
Los Angeles, California, United States
Active, not recruiting - Hoag Memorial Hospital Presbyterian
Newport Beach, California, United States
Active, not recruiting - Uc Davis Medical Center Sacramento
Sacramento, California, United States
Active, not recruiting - Bay Area Structural Heart at Sutter Health
San Francisco, California, United States
Recruiting - Kaiser San Francisco Medical Center
San Francisco, California, United States
Active, not recruiting - Stanford University
Stanford, California, United States
Active, not recruiting - Uc Health Northern Colorado (medical Center of the Rockies)
Loveland, Colorado, United States
Active, not recruiting - Hartford Hospital
Hartford, Connecticut, United States
Active, not recruiting - Naples Community Hospital Healthcare System
North Naples, Florida, United States
Active, not recruiting - Emory University Atlanta
Atlanta, Georgia, United States
Active, not recruiting - Piedmont Heart Institute
Atlanta, Georgia, United States
Active, not recruiting - Rush University Medical Center Chicago
Chicago, Illinois, United States
Active, not recruiting - Alexian Brothers Hospital Network
Elk Grove Village, Illinois, United States
Recruiting - Northshore University Healthsystem Research Institute Evanston
Evanston, Illinois, United States
Active, not recruiting - Northwestern University Chicago
Evanston, Illinois, United States
Active, not recruiting - Silver Cross Hospital
New Lenox, Illinois, United States
Recruiting - St. Vincent Medical Group, Inc./ St. Vincent Heart Center of Indiana, Llc
Carmel, Indiana, United States
Active, not recruiting - University of Kansas Medical Center
Kansas City, Kansas, United States
Active, not recruiting - Ascension Via Christi St. Francis (cardiovascular Research Institute of Kansas)
Wichita, Kansas, United States
Recruiting - Medstar Union Memorial Hospital
Baltimore, Maryland, United States
Recruiting - Brigham and Women'S Hospital
Boston, Massachusetts, United States
Active, not recruiting - Henry Ford Hospital
Detroit, Michigan, United States
Active, not recruiting - Mayo Clinic Rochester
Rochester, Minnesota, United States
Active, not recruiting - Centracare Heart and Vascular Center
Saint Cloud, Minnesota, United States
Active, not recruiting - Saint Luke'S Hospital
Kansas City, Missouri, United States
Active, not recruiting - Washington University - Barnes-Jewish Hospital Saint Louis
St Louis, Missouri, United States
Active, not recruiting - St. Patrick Hospital
Missoula, Montana, United States
Active, not recruiting - Dartmouth-Hitchcock Medical Center, Hanover
Lebanon, New Hampshire, United States
Recruiting - Atlantic Health System Morristown
Morristown, New Jersey, United States
Recruiting - Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey, United States
Recruiting - the Valley Hospital
Ridgewood, New Jersey, United States
Active, not recruiting
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 20 Jun 2022
- Primary completion
- 31 Jul 2027
- Completion
- 31 Jan 2037
- Last update posted
- 11 Aug 2026
- Registered enrollment
- 1,234
- Registry id
- NCT05172960
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.