SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Summary
The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- David Kandzari, MD
Piedmont Heart Institute
Principal Investigator - Felix Mahfoud, MD
Saarland University Hospital
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
100 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- the Alfred Hospital
Melbourne, Victoria, Australia
- Royal Perth Hospital (dobney Hypertension Centre)
Perth, Western Australia, Australia
- Algemeen Stedelijk Ziekenhuis - R&d Hartziekten
Aalst, Oost - Vlaanderen, Belgium
- Az Sint Jan Brugge-Oostende Av
Bruges, Belgium
- Ziekenhuis Oost Limburg - Campus Sint-Jan
Genk, Belgium
- University Hospital Ghent
Ghent, Belgium
- Chc Montlegia
Liège, Belgium
- Hôpital Saint André -Centre Hospitalier Universitaire de Bordeaux
Bordeaux, France
- Hôpital Pitié Salpêtrière
Paris, France
- Uniklinik Erlangen
Erlangen, Germany
- Justus-Liebig-Universität Gießen
Giessen, Germany
- Universitatsklinikum Des Saarlandes
Homburg, Germany
- Herzzentrum Leipzig
Leipzig, Germany
- Sana Kliniken Lübeck Gmbh
Lübeck, Germany
- Hippokration General Hospital of Athens
Athens, Greece
- Mater Misericordiae University Hospital
Dublin, Ireland
- Centre Hospitalier Princesse Grace
Monaco, Monaco
- Zuyderland Medisch Centrum Heerlen
Heerlen, Netherlands
- Erasmus Universtiy Medical Center
Rotterdam, Netherlands
- Danderyd Sjukhus
Stockholm, Sweden
- John Radcliffe Hospital
Oxford, Oxfordshire, United Kingdom
- University of Alabama at Birmingham (uab) Hospital
Birmingham, Alabama, United States
- Banner Heart Hospital
Mesa, Arizona, United States
- Abrazo Arizona Heart Hospital/biltmore Cardiology
Phoenix, Arizona, United States
- Honorhealth Research Institute
Scottsdale, Arizona, United States
- Arkansas Cardiology
Little Rock, Arkansas, United States
- Scripps Memorial Hospital
La Jolla, California, United States
- University of California, San Francisco
San Francisco, California, United States
- Stanford Hospital and Clinics
Stanford, California, United States
- University of Colorado Anschutz Medical Campus
Aurora, Colorado, United States
- Colorado Heart and Vascular Pc
Lakewood, Colorado, United States
- Hartford Hospital
Hartford, Connecticut, United States
- Medstar Washington Hospital Center
Washington D.C., District of Columbia, United States
- Baycare Health System
Clearwater, Florida, United States
- Clearwater Cardiovascular Consultants
Clearwater, Florida, United States
- Baptist Medical Center
Jacksonville, Florida, United States
- University of Miami Hosptial
Miami, Florida, United States
- Adventhealth Orlando
Orlando, Florida, United States
- Orlando Health Heart & Vascular Institute
Orlando, Florida, United States
- Baycare Medical Group
Safety Harbor, Florida, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 20 Oct 2021
- Primary completion
- 30 Nov 2026
- Completion
- 30 Nov 2029
- Last update posted
- 5 May 2026
- Registered enrollment
- 1,899
- Registry id
- NCT05198674
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.