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Clinical trialNCT05228015TerminatedPhase 1Interventional

Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects with Advanced Solid Tumors

SponsorIkena OncologyEnrollment67Epithelioid Hemangioendothelioma (EHE)Malignant Pleural Mesothelioma (MPM)NF2 DeficiencyNF2 Deficient MesotheliomaOther NF2 Deficient Solid Tumors and Solid Tumors with YAP1/TAZ Fusion GenesSolid Tumor+2 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Peninsula South Eastern Haematology and Oncology Group (paso Medical)

    Frankston, Victoria, Australia

United Kingdom
  • University Hospitals of Leicester Nhs Trust

    Leicester, England, United Kingdom

  • the Royal Marsden Hospital

    London, England, United Kingdom

United States
  • the University of Chicago

    Chicago, Illinois, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, United States

  • Start Midwest

    Grand Rapids, Michigan, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • Sidney Kimmel Cancer Center at Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, United States

  • University of Pennsylvania Abramson Cancer Center

    Philadelphia, Pennsylvania, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

  • Next Oncology

    San Antonio, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
7 Jan 2022
Primary completion
27 Aug 2024
Completion
9 Sept 2024
Last update posted
18 Nov 2024
Registered enrollment
67
Registry id
NCT05228015

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.