FindMyKOL
Clinical trialNCT05238831WithdrawnEarly phase 1Interventional

SMMART Adaptive Clinical Treatment (ACT) Trial

SponsorOHSU Knight Cancer InstituteEnrollment0Advanced Breast CarcinomaAdvanced Malignant Solid NeoplasmAdvanced Ovarian CarcinomaAdvanced Pancreatic CarcinomaAdvanced Prostate CarcinomaAdvanced Sarcoma+11 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

SMMART-ACT is a feasibility pilot study to determine if testing samples from a participant's cancer using a precision medicine approach can be used to identify specific drugs or drug combinations that can help control their disease. The safety and tolerability of the drug or drug combination is also to be studied. Another purpose is for researchers to study tumor cells to try to learn why some people respond to a certain therapy and others do not, and why some cancer drugs stop working. The study population will include participants with advanced breast, ovarian, prostate, or pancreatic malignancies, or sarcomas.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Alectinib →Alpelisib →Anastrozole →Atezolizumab →Bevacizumab →Capecitabine →Carboplatin →Cobimetinib →Entrectinib →Eribulin →Fulvestrant →Hyaluronidase →Irinotecan →Letrozole →Paclitaxel →Niraparib →Olaparib →Palbociclib →Pertuzumab →Trastuzumab →Vemurafenib →Vinorelbine →Vismodegib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jan 2023
Primary completion
31 May 2026
Completion
31 May 2026
Last update posted
23 Jan 2024
Registered enrollment
0
Registry id
NCT05238831
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.