Clinical trialNCT05248230RecruitingPhase 2Interventional

4D-710 in Adult Patients With Cystic Fibrosis

Sponsor4D Molecular TherapeuticsEnrollment30Cystic Fibrosis Lung

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Sam Moskowitz MD
4D Molecular Therapeutics
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

20 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama Child Health Research Unit
Birmingham, Alabama, United States
George M. Solomon, MD
Recruiting
the University of Arizona
Tucson, Arizona, United States
Cori L Daines, MD
Recruiting
University of California San Francisco
San Francisco, California, United States
Jonathan Singer, MD
Recruiting
National Jewish Health
Denver, Colorado, United States
Jennifer Taylor-Cousar, MD
Recruiting
University of Florida
Gainesville, Florida, United States
Cesar Trillo-Alvarez, MD
Recruiting
University of Miami Hospital
Miami, Florida, United States
Maria G Tupayachi Ortiz, MD
Recruiting
Northwestern Memorial Hospital
Chicago, Illinois, United States
Manu Jain, MD
Recruiting
University of Kansas Medical Center
Kansas City, Kansas, United States
Joel Mermis, MD
Recruiting
Johns Hopkins Hospital
Baltimore, Maryland, United States
Noah Lechtzin, MD
Recruiting
Boston Children'S Hospital
Boston, Massachusetts, United States
Alicia Casey, MD
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Allen Lapey, MD
Recruiting
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Completed
Rainbow Babies and Children'S Hospital/university Hospitals Cleveland Medical Center
Cleveland, Ohio, United States
Alex Gifford, MD
Recruiting
Nationwide Children'S Hospital
Columbus, Ohio, United States
Karen S. McCoy, MD
Recruiting
Penn State Health
Hershey, Pennsylvania, United States
Withdrawn
the Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Daniel Dorgan, MD
Recruiting
Medical University of South Carolina
Charleston, South Carolina, United States
Patrick Flume, MD
Recruiting
the University of Texas Southwestern Medical Center
Dallas, Texas, United States
Raksha Jain, MD
Recruiting
Virginia Commonwealth University Health System
Richmond, Virginia, United States
Nauman A. Chaudary, MD
Recruiting
University of Washington Medical Center
Seattle, Washington, United States
Christopher Goss, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

4D-710

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 29 Mar 2022
Primary completion: 30 Jun 2027
Completion: 30 Jun 2031
Last update posted: 6 Jul 2026
Registered enrollment: 30
Registry id: NCT05248230

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.