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Clinical trialNCT05252754RecruitingPhase 3Interventional

Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis

SponsorJohns Hopkins UniversityEnrollment4,874Post-ERCP Acute Pancreatitis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This research is being done to see if using oral tacrolimus before endoscopy, can prevent pancreatitis that may occur after ERCP (a type of gastrointestinal endoscopy).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

India
  • Asian Institute of Gastroenterology

    Hyderabad, Andhra Pradesh, India

    Recruiting
  • Apollo Multispecialty Hospitals,

    Kolkata, West Bengal, India

    Not, yet, recruiting
  • Post Graduate Institute of Medical Education and Research

    Chandigarh, India

    Not, yet, recruiting
Singapore
  • Singapore General Hospital

    Singapore, Singapore

    Not, yet, recruiting
United States
  • Johns Hopkins Hospital

    Baltimore, Maryland, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboRectal IndomethacinTacrolimus
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
18 Jan 2023
Primary completion
31 Dec 2026
Completion
31 Dec 2026
Last update posted
9 Dec 2025
Registered enrollment
4,874
Registry id
NCT05252754

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.