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Clinical trialNCT05255445CompletedObservational

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients

SponsorWestatEnrollment157Pediatric CancerSickle Cell DiseaseThalassemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused recipients (RBC-IMPACT) is an observational cohort study to assess donor, component, and recipient factors that contribute to RBC efficacy in chronically and episodically transfused patients. The objective of the study is to determine how specific genetic and non-genetic factors in donors and recipients may impact RBC survival after transfusion - in short, what factors on both the donor and recipient side may improve the efficacy of the transfusion.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Brazil
  • Hemoam - Amazonas

    Manaus, Amazonas, Brazil

  • Hemominas - Minas Gerais

    Belo Horizonte, Minas Gerais, Brazil

  • Hemope - Pernambuco

    Recife, Pernambuco, Brazil

  • Hemorio - Rio de Janeiro

    Rio de Janeiro, Brazil

  • Childrens Institute and Adult Clinics at Hospital Das Clínicas Da Faculdade de Medicina Da Universidade de São Paulo

    São Paulo, Brazil

United States
  • Ucsf Benioff Children'S Hospital

    Oakland, California, United States

  • Vitalant Research Institute

    San Francisco, California, United States

  • Boston Children'S Hospital

    Boston, Massachusetts, United States

  • Columbia University Irving Medical Center/new York Presbyterian Hospital (nyph)

    New York, New York, United States

  • New York Blood Center (nybc)

    New York, New York, United States

  • Weill Cornell Medical Collection (wcmc)/new York Presbyterian Hospital (nyph)

    New York, New York, United States

  • Children'S Wisconsin

    Milwaukee, Wisconsin, United States

  • Froedtert Hospital

    Milwaukee, Wisconsin, United States

  • Versiti Wisconsin, Inc.

    Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Red Blood Cell Transfusion
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
16 Mar 2022
Primary completion
31 Mar 2024
Completion
31 Mar 2024
Last update posted
17 May 2024
Registered enrollment
157
Registry id
NCT05255445
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.