Clinical trialNCT05281471RecruitingPhase 3Interventional

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

SponsorGenelux CorporationEnrollment186Endometrioid Ovarian CancerFallopian Tube CancerHigh-grade Serous Ovarian CancerOvarian Clear Cell CarcinomaPlatinum-refractory Ovarian CancerPlatinum-resistant Ovarian Cancer+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Robert W. Holloway, MD
AdventHealth Cancer Institute
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

32 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

the University of South Alabama, Mitchell Cancer Institute
Mobile, Alabama, United States
Jennifer Pierce, MD
Recruiting
University of Arizona Cancer Center
Tucson, Arizona, United States
Setsuko K. Chambers, MD
Recruiting
City of Hope
Duarte, California, United States
Edward Wang, MD, PhD
Recruiting
Uc San Diego Health - Moores Cancer Center
La Jolla, California, United States
Michael McHale, MDRamez Eskander, MD
Recruiting
Hoag Gynecologic Oncology
Newport Beach, California, United States
Alberto Mendivil, MD
Recruiting
Uci Health Chao Family Comprehensive Cancer Center
Orange, California, United States
Krishnansu S. Tewari, MD
Recruiting
Adventhealth Cancer Institute
Orlando, Florida, United States
Robert W Holloway, MD
Recruiting
Sarasota Memorial Healthcare System
Sarasota, Florida, United States
Beverly Long, MD
Recruiting
Women'S Cancer Associates With Women'S Care Florida
St. Petersburg, Florida, United States
Megan Indermaur, MD
Recruiting
Emory University
Atlanta, Georgia, United States
Jennifer Scalici, MD
Recruiting
Indiana University Simon Comprehensive Cancer Center
Indianapolis, Indiana, United States
Jessica E. Parker, MD
Recruiting
Holy Cross Hospital
Silver Spring, Maryland, United States
Frederick D Min, MDJasmine Ebott, MD
Recruiting
University of Michigan
Ann Arbor, Michigan, United States
Jean Siedel, MD
Recruiting
Karmanos Cancer Institute
Detroit, Michigan, United States
Robert Morris, MD
Recruiting
Mercy Hospital St. Louis
St Louis, Missouri, United States
Madhavi Manyam, MD
Recruiting
Washington University School of Medicine
St Louis, Missouri, United States
Premal Thaker, MD
Recruiting
Women'S Cancer Center of Nevada
Las Vegas, Nevada, United States
Nicola M. Spirtos, MD
Recruiting
Center of Hope
Reno, Nevada, United States
Peter Lim, MD
Recruiting
Stony Brook Cancer Center
Stony Brook, New York, United States
Gabrielle Gossner, MD
Recruiting
Levine Cancer Institute
Charlotte, North Carolina, United States
Erin K Crane, MD
Recruiting
East Carolina University
Greenville, North Carolina, United States
Grainger Lanneau, MD
Recruiting
Cleveland Clinic
Cleveland, Ohio, United States
Peter Rose, MD
Recruiting
Ohiohealth Research Institute
Columbus, Ohio, United States
Aine Clements, MD
Recruiting
Kettering Health
Kettering, Ohio, United States
Thomas J. Reid, MD
Recruiting
Promedica Flower Hospital
Sylvania, Ohio, United States
Adam Walter, MD
Recruiting
Oklahoma University Health Stephenson Cancer Center
Oklahoma City, Oklahoma, United States
Debra Richardson, MD
Recruiting
Ahn West Penn Hospital
Pittsburgh, Pennsylvania, United States
Sarah Crafton, MD
Recruiting
Hollings Cancer Center
Charleston, South Carolina, United States
Brian Orr, MD
Recruiting
Erlanger Health, Inc.
Chattanooga, Tennessee, United States
Stephen DePasquale, MD
Recruiting
Baylor College of Medicine
Houston, Texas, United States
Jan Sunde, MD
Recruiting
University of Texas Science Center at Houston, Mcgovern Medical School
Houston, Texas, United States
Joseph Lucci, III, MD
Recruiting
Providence Sacred Heart Medical Center & Children'S Hospital
Spokane, Washington, United States
Melanie Bergman, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2022
Primary completion: 31 Dec 2026
Completion: 31 Dec 2027
Last update posted: 10 Jul 2026
Registered enrollment: 186
Registry id: NCT05281471

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.