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Clinical trialNCT05309655Active, not recruitingInterventional

Cardiac Outcomes With Near-Complete Estrogen Deprivation

SponsorDuke UniversityEnrollment90Breast CancerCardiovascular ComplicationsTriple Negative Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this research study is to understand what effect near complete estrogen deprivation (NCED) therapy has on the heart in breast cancer patients. Investigators want to understand if NCED changes how the heart works.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Duke Cancer Center

    Durham, North Carolina, United States

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, North Carolina, United States

  • Virginia Commonwealth University Massey Cancer Center

    Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Adenosine Stress Cardiac Magnetic Resonance Imaging
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
2 Sept 2022
Primary completion
1 May 2028
Completion
1 Dec 2028
Last update posted
5 Aug 2026
Registered enrollment
90
Registry id
NCT05309655
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.