FindMyKOL
Clinical trialNCT05325632RecruitingPhase 2Interventional

Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab

SponsorH. Lee Moffitt Cancer Center and Research InstituteEnrollment53HER2-positive Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the study is to find out if an investigational drug called Dendritic Cell (DC1) vaccine added to standard neoadjuvant (given before main treatment) therapy can help people with HER2 (human epidermal growth factor receptor 2) positive breast cancer.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Moffitt Cancer Center

    Tampa, Florida, United States

    Aixa Soyano Muller, MDAvan Armaghani, MDBrian Czerniecki, MD, PhDChristine Sam, MDHatem Soliman, MDHung Khong, MDHyo Han, MDKimberley Lee, MD, MHSLoretta Loftus, MD, MBAMartine Extermann, MD, PhDRicardo Costa, MD, MSc
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

HER-2 pulsed DC1Paclitaxel →Pertuzumab →Trastuzumab →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
28 Oct 2021
Primary completion
28 Feb 2027
Completion
30 Sept 2027
Last update posted
2 Mar 2026
Registered enrollment
53
Registry id
NCT05325632
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.