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Clinical trialNCT05337553Active, not recruitingPhase 3Interventional

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy

SponsorBiohaven Pharmaceuticals, Inc.Enrollment269Neuromuscular DiseasesSMASpinal Muscular Atrophy
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

53 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium
  • University Hospital Antwerp

    Edegem, Belgium

  • University Hospital Ghent

    Ghent, Belgium

  • University Hospital Leuven

    Leuven, Belgium

Czechia
  • University Hospital Brno - Dept. of Pediatric Neurology

    Brno, Czechia

  • Motol University Hospital

    Prague, Czechia

Germany
  • University Hospital Essen (public-Law Institution) - Dept. of Pediatrics I

    Essen, Germany

  • University Hospital Freiburg, Center for Children and Adolescent Medicine, Dept. of Neuropediatrics and Muscle Disorders

    Freiburg im Breisgau, Germany

  • Dr. Von Haunersches Children'S Hospital - Lmu Munich

    Munich, Germany

Italy
  • Irccs Institute of Neurological Sciences of Bologna - Bellaria Hospital

    Bologna, Italy

  • Nemo-Brescia Clinical Center for Neuromuscular Diseases

    Gussago, Italy

  • Irccs Neurological Institute C. Mondino Child and Neuropsychiatric Unit

    Pavia, Italy

  • Bambino Gesù Children'S Research Hospital Irccs - San Paolo Office Dept. of Neuroscience

    Roma, Italy

Netherlands
  • University Medical Center Utrecht

    Utrecht, Netherlands

Poland
  • University Clinical Centre in Gdansk - Dept. of Developmental Neurology

    Gdansk, Poland

  • Heliodor Swiecicki Clinical Hospital at Medical University - Child and Adolescents Neurology Clinic

    Poznan, Poland

  • the Children'S Memorial Health Institute - Dept. of Neurology and Epileptology

    Warsaw, Poland

  • T. Marciniak Lower Silesian Specialist Hospital, Pediatric Neurology Dept.

    Wroclaw, Poland

Spain
  • Donostia University Hospital

    Donostia / San Sebastian, Spain

  • Hospital Sant Joan de Déu

    Esplugues de Llobregat, Spain

  • Maternal-Child'S Hospital of Málaga, Regional University Hospital - Pediatric Neurology Unit

    Málaga, Spain

  • la Fe University and Polytechnic Hospital

    Valencia, Spain

United Kingdom
  • Royal Hospital for Children

    Glasgow, Scotland, United Kingdom

  • John Radcliffe Hospital

    Oxford, United Kingdom

United States
  • Phoenix Children'S

    Phoenix, Arizona, United States

  • Ucsd & Rady Children'S

    La Jolla, California, United States

  • Children'S Hospital of Los Angeles

    Los Angeles, California, United States

  • Ucsf Benioff Children'S Hospital, Medical Center

    San Francisco, California, United States

  • Children'S Hospital Colorado

    Aurora, Colorado, United States

  • Uf Health, Shands Hospital

    Gainesville, Florida, United States

  • Rare Disease Research

    Atlanta, Georgia, United States

  • Northwestern University - Feinberg School of Medicine - Ann & Robert H. Lurie Children'S Hospital of Chicago

    Chicago, Illinois, United States

  • Indiana University -Riley Research

    Indianapolis, Indiana, United States

  • University of Iowa

    Iowa City, Iowa, United States

  • University of Kansas Medical Center

    Fairway, Kansas, United States

  • Boston Children'S Hospital - Harvard

    Boston, Massachusetts, United States

  • Bshs Office of Research

    Grand Rapids, Michigan, United States

  • Washington University in St. Louis

    St Louis, Missouri, United States

  • Columbia University Medical Center

    New York, New York, United States

  • Stony Brook University Hospital

    Stony Brook, New York, United States

  • Duke University Medicine

    Durham, North Carolina, United States

13 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
6 Jul 2022
Primary completion
25 Sept 2024
Completion
31 Dec 2027
Last update posted
1 Jun 2026
Registered enrollment
269
Registry id
NCT05337553

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.