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Clinical trialNCT05361382Active, not recruitingPhase 1Interventional

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease

SponsorTharick PascoalEnrollment822Alzheimer Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to compare/harmonize cross-sectional and longitudinal tau tangle measurements obtained with the tau PET radiopharmaceuticals Flortaucipir and MK-6240 to elucidate the advantages and caveats of their use in clinical trials/practice and provide parameters to integrate their estimates.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Mcgill University

    Montreal, Quebec, Canada

Spain
  • Sant Pau Biomedical Research Institute

    Barcelona, Spain, Spain

United States
  • Lawrence Berkeley National Laboratory

    Berkeley, California, United States

  • University of California San Francisco

    San Francisco, California, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Washington University in St. Louis

    St Louis, Missouri, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, United States

  • Brown University

    Providence, Rhode Island, United States

  • Houston Methodist Neurological Institute

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

18F-Flortaucipir radiopharmaceutical18F-MK-6240 radiopharmaceuticalAmyloid-β radiopharmaceutical
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
2 Mar 2022
Primary completion
31 May 2027
Completion
31 May 2027
Last update posted
29 Oct 2025
Registered enrollment
822
Registry id
NCT05361382
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.