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Clinical trialNCT05364021CompletedPhase 1/PHASE2Interventional

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

SponsorLongboard PharmaceuticalsEnrollment52Developmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objective of this study is to assess the safety, tolerability, efficacy, and pharmacokinetics of adjunctive therapy of LP352 in adults and adolescents with developmental and epileptic encephalopathies.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

34 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Royal Brisbane Women'S Hospital

    Herston, Queensland, Australia

  • Queensland Children'S Hospital

    South Brisbane, Queensland, Australia

  • Monash Children'S Hospital, Monash Health

    Clayton, Victoria, Australia

  • Austin Health

    Heidelberg, Victoria, Australia

  • Alfred Health

    Melbourne, Victoria, Australia

United States
  • University of Arizona - Health Sciences Center

    Tucson, Arizona, United States

  • Arkansas Children'S Hospital

    Little Rock, Arkansas, United States

  • Rancho Los Amigos National Rehabilitation Center (rlanrc)

    Downey, California, United States

  • Children'S Hospital of Orange County

    Orange, California, United States

  • University of California San Francisco

    San Francisco, California, United States

  • Northwest Florida Clinical Research Group

    Gulf Breeze, Florida, United States

  • University of Miami

    Miami, Florida, United States

  • Advent Health Orlando

    Orlando, Florida, United States

  • Research Institute of Orlando

    Orlando, Florida, United States

  • University of South Florida

    Tampa, Florida, United States

  • Hawaii Pacific Neuroscience

    Honolulu, Hawaii, United States

  • Consultants in Epilepsy and Neurology

    Boise, Idaho, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, United States

  • Mid-Atlantic Epilepsy and Sleep Center

    Bethesda, Maryland, United States

  • Spectrum Health

    Grand Rapids, Michigan, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Boston Children'S Health Physicians Llp

    Hawthorne, New York, United States

  • New York University Langone Hospital - Long Island

    Mineola, New York, United States

  • Northwell Health

    New York, New York, United States

  • Northeast Regional Epilepsy Group

    Staten Island, New York, United States

  • Onsite Clinical Solutions Llc

    Charlotte, North Carolina, United States

  • Wake Forest University School of Medicine

    Winston-Salem, North Carolina, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, United States

  • Providence Neurological Specialties-East

    Portland, Oregon, United States

  • Austin Epilepsy Care Center

    Austin, Texas, United States

  • Child Neurology Consultants of Austin

    Austin, Texas, United States

  • University of Utah

    Salt Lake City, Utah, United States

  • University of Washington Valley Medical Center

    Renton, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

LP352Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
3 Mar 2022
Primary completion
16 Nov 2023
Completion
20 Nov 2023
Last update posted
8 Nov 2024
Registered enrollment
52
Registry id
NCT05364021

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.