Clinical trialNCT05374109CompletedInterventional

SYV: A Mental Health Intervention to Improve HIV Outcomes in Tanzanian Youth

SponsorDuke UniversityEnrollment690Adherence, MedicationHIV-1-infectionMental Health Issue

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The overall objectives of this proposal are to support positive coping strategies that bolster mental health and lead to improved HIV outcomes among Young People Living with HIV (YPLWH). The central hypothesis is that SYV (Sauti ya Vijana, The Voice of Youth) will be effective to improve antiretroviral therapy (ART) adherence and virologic suppression in YPLWH in Tanzania. The rationale for this project is that by targeting mental health, which is strongly associated with medication adherence, that this will effectively improve adherence and thereby HIV viral suppression. The central hypothesis will be tested in three aims in a hybrid type-1 effectiveness-implementation trial.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Dorothy E Dow, MD
Duke University
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Tanzania

Chronic Disease Clinic of Ifakara Health Institute
Ifakara, Tanzania
Baylor College of Medicine Children'S Foundation - Tanzania, Mbeya Centre for Excellence
Mbeya, Tanzania
Kilimanjaro Christian Medical Centre
Moshi, Tanzania
Mawenzi Regional Referral Hospital
Moshi, Tanzania
Baylor College of Medicine Children'S Foundation - Tanzania, Mwanza Centre for Excellence
Mwanza, Tanzania
Bugando Medical Centre
Mwanza, Tanzania

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Mar 2023
Primary completion: 20 Dec 2024
Completion: 15 Dec 2025
Last update posted: 29 Jul 2026
Registered enrollment: 690
Registry id: NCT05374109

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.