Clinical trialNCT05378347RecruitingInterventional

Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

SponsorMedtronic CardiovascularEnrollment600Abdominal Aortic AneurysmAbdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Excluder / Excluder Conformable AAA Endoprosthesis in subjects with Abdominal Aortic Aneurysms. Subjects are randomized and imaging collected at all follow-up time points to assess the primary endpoint.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Hence Verhagen, MD
Erasmus University Medical Center, Netherlands
Principal Investigator
clinicaltrials.gov ↗
Marc Schermerhorn, MD
Beth Israel Deaconess Medical Center, United States
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

68 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Finland

Helsinki University Hospital
Helsinki, Finland
Maarit Venermo, MD, PhD
Recruiting
Kuopio University Hospital
Kuopio, Finland
Petri Saari, MD
Recruiting

France

Assistance Publique - Hopitaux de Marseille Hopital de la Timone
Marseille, Marseille Cedex, France
Mariangela De Masi, MD
Recruiting
Chu Clermont-Ferrand
Clermont-Ferrand, France
Fabien Thaveau, MD, PhD
Recruiting
Hospices Civils de Lyon-Chu Lyon
Lyon, France
Withdrawn
Hopital de Hautepierre - Chu de Strasbourg
Strasbourg, France
Nabil Chakfe, MD, PhD
Recruiting

Germany

University Hospital Augsburg
Augsburg, Germany
Alexander Hyhlik-Duerr, MD, PhD
Recruiting
University Hospital Cologne
Cologne, Germany
Bernhard Dorweiler, MD, PhD
Recruiting
Elisabeth Hospital Essen
Essen, Germany
Johannes Hoffman, MD
Recruiting
Universitatsklinikum Frankfurt
Frankfurt, Germany
Kyriakos Oikonomou, MD, PhD
Recruiting
University Hospital Leipzig
Leipzig, Germany
Andrej Schmidt, MD
Recruiting
University Hospital Rechts Der Isar of the Technical University Munich
Munich, Germany
Daniela Branzan, MD
Recruiting
St. Franziskus Hospital Munster
Münster, Germany
Martin Austermann, MD
Recruiting

Greece

University Hospital of Larisa
Larissa, Greece
Recruiting

Italy

Fondazione Irccs Ca' Granda - Ospendale Maggiore Policlinico
Milan, Italy
Chiara Lomazzi, MD
Recruiting
Azienda Ospedaliera Universitaria Federico Ii
Naples, Italy
Umberto Marcello Bracale, MD, PhD
Recruiting
Aou Citta Della Salute E Della Scienza Di Torino
Torino, Italy
Fabio Verzini, MD, PhD, FEBVS
Recruiting

Japan

Nagoya University Hospital
Nagoya, Aichi-ken, Japan
Hirosho Banno, MD, PhD
Recruiting
Asahikawa Medical University Hospital
Asahikawa, Hokkaido, Japan
Daiki Uchida, MD, PhD
Recruiting
Niigata University Medical and Dental Hospital
Chuo Ku, Niigata, Japan
Takeshi Okamoto, MD, PhD
Recruiting
Hamamatsu University Hospital
Hamamatsu, Shizuoka, Japan
Norihiko Shiiya, MD, PhD
Recruiting
Keio University Hospital
Shinjuku-Ku, Tokyo, Japan
Hideyuki Shimizu, MD, PhD
Recruiting
Osaka Keisatsu Hospital
Osaka, Japan
Toru Kuratani
Recruiting

Netherlands

Rijnstate Hospital
Arnhem, The Netherlands, Netherlands
Michel Reijnen, MD, PhD
Recruiting
Amsterdam University Medical Center
Amsterdam, Netherlands
Recruiting
Catharina Ziekenhuis
Eindhoven, Netherlands
Philippe Cuypers, MD, PhD
Recruiting
Erasmus Medisch Centrum
Rotterdam, Netherlands
Hence Verhagen, MD, PhD
Recruiting

Spain

Hospital Universitario Son Espases
Palma, Mallorca, Spain
Pascual Lozano-Vilardell, MD
Recruiting

Switzerland

Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland
Sebastien Deglise, MD, PhD
Recruiting
Luzerner Kantonsspital
Lucerne, Switzerland
Maani Hakimi, MD, PhD
Recruiting

Taiwan

China Medical University Hospital
Taichung, Taiwan
You-Cian Lin, MD, PhD
Recruiting
Chi Mei Medical Center
Tainan, Taiwan
Nan-Chun Wu, MD
Recruiting
National Taiwan University Hospital
Taipei, Taiwan
I-Hui Wu, MD, PhD
Recruiting
Taipei Veterans General Hospital
Taipei, Taiwan
I-Ming Chen, MD, PhD
Recruiting

United Kingdom

Oxford University Hospitals Nhs Trust - John Radcliffe Hospital
Oxford, Oxfordshire, United Kingdom
Dominic Howard, BM B.Ch MA DPhil (Oxon) FRCS
Recruiting
Royal Infirmary of Edinburgh
Edinburgh, United Kingdom
Andrew Tambyraja, MD
Recruiting

United States

Loma Linda University Medical Center
Loma Linda, California, United States
Ahmed Abou-Zamzam, MD
Recruiting
Hoag Hospital
Newport Beach, California, United States
Allen Murga
Recruiting
University of California Irvine Medical Center
Orange, California, United States
Anthony Chau, MD
Recruiting
University of California Davis Medical Center
Sacramento, California, United States
Withdrawn

28 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Jan 2023
Primary completion: 31 May 2027
Completion: 31 May 2031
Last update posted: 6 Jul 2026
Registered enrollment: 600
Registry id: NCT05378347

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.