Clinical trialNCT05451004RecruitingPhase 3Interventional

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

SponsorCanadian Cancer Trials GroupEnrollment510Oropharyngeal Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT), compared to the usual treatment when radiotherapy is given to both sides of the neck?

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Ali Hosni
University Health Network, Princess Margaret Hospital, Toronto ON Canada
Study Chair
clinicaltrials.gov ↗
John R de Almeida
University Health Network, Princess Margaret Hospital, Toronto ON Canada
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

38 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Bcca-Vancouver Cancer Centre
Vancouver, British Columbia, Canada
Eric Tran
Recruiting
Cancercare Manitoba
Winnipeg, Manitoba, Canada
Carlton Johnny John Pandian
Recruiting
Health Sciences North
Greater Sudbury, Ontario, Canada
Mirko Manojlovic Kolarski
Recruiting
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada
Nhu Tram A. Nguyen
Recruiting
Saint Joseph'S Healthcare Charlton Campus
Hamilton, Ontario, Canada
Suspended
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Suspended
University Health Network-Princess Margaret Hospital
Toronto, Ontario, Canada
Ali Hosni
Recruiting
Chum - Centre Hospitalier de L'Universite de Montreal
Montreal, Quebec, Canada
Apostolos Christopoulos
Recruiting
Jewish General Hospital
Montreal, Quebec, Canada
Active, not recruiting
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Sherbrooke, Quebec, Canada
Isabelle Gauthier
Recruiting

United States

City of Hope Corona
Corona, California, United States
Krupal B. Patel
Recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Krupal B. Patel
Recruiting
City of Hope at Irvine Lennar
Irvine, California, United States
Suspended
Um Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States
Gregory J. Kubicek
Recruiting
Baptist Md Anderson Cancer Center
Jacksonville, Florida, United States
Active, not recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States
Gregory J. Kubicek
Recruiting
Moffitt Cancer Center
Tampa, Florida, United States
Deepa Danan
Recruiting
Moffitt Cancer Center - Mckinley Campus
Tampa, Florida, United States
Deepa Danan
Recruiting
Moffitt Cancer Center-International Plaza
Tampa, Florida, United States
Deepa Danan
Recruiting
Emory University Hospital Midtown
Atlanta, Georgia, United States
James E. Bates
Recruiting
Northwestern University
Chicago, Illinois, United States
Active, not recruiting
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, United States
Active, not recruiting
the James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, United States
Suspended
University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, United States
David W. Forner
Recruiting
University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan, United States
David W. Forner
Recruiting
Henry Ford Hospital
Detroit, Michigan, United States
Samantha H. Tam
Recruiting
Mu Health - University Hospital/ellis Fischel Cancer Center
Columbia, Missouri, United States
Patrick Tassone
Recruiting
Unc Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States
Colette Shen
Recruiting
Metrohealth Medical Center
Cleveland, Ohio, United States
Akash N. Naik
Recruiting
Providence Portland Medical Center
Portland, Oregon, United States
Charles W. Drescher
Recruiting
Ut Md Anderson - the Woodlands
Conroe, Texas, United States
Anna Lee
Recruiting
Ut Md Anderson - West Houston
Houston, Texas, United States
Anna Lee
Recruiting
Ut Md Anderson Cancer Center
Houston, Texas, United States
Anna Lee
Recruiting
Ut Md Anderson - League City
League City, Texas, United States
Anna Lee
Recruiting
Ut Md Anderson - Sugar Land
Sugar Land, Texas, United States
Anna Lee
Recruiting
Central Vermont Medical Center/national Life Cancer Treatment
Berlin Corners, Vermont, United States
Mark H. Sueyoshi
Recruiting
University of Vermont Medical Center
Burlington, Vermont, United States
Mark H. Sueyoshi
Recruiting
University of Vermont and State Agricultural College
Burlington, Vermont, United States
Mark H. Sueyoshi
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 10 Feb 2023
Primary completion: 30 Aug 2030
Completion: 30 Aug 2031
Last update posted: 14 Jul 2026
Registered enrollment: 510
Registry id: NCT05451004

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.