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Clinical trialNCT05500508TerminatedPhase 1/PHASE2Interventional

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

SponsorAminex Therapeutics, Inc.Enrollment15Advanced CancerBreast CancerCancerCervical CancerColorectal CancerDIPG Brain Tumor+14 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A Phase 1B/2A study will be conducted to establish safety and dose level of AMXT 1501 dicaprate in combination with IV DFMO, in cancer patients.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Kids Cancer Centre

    Sydney, New South Wales, Australia

United States
  • Mayo Clinic - Arizona

    Phoenix, Arizona, United States

  • Mayo Clinic - Florida

    Jacksonville, Florida, United States

  • Mayo Clinic - Minnesota

    Rochester, Minnesota, United States

  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

  • Md Anderson Cancer Center

    Houston, Texas, United States

  • Fred Hutch Cancer Center - Seattle Cancer Care Alliance

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AMXT1501Eflornithine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 Nov 2022
Primary completion
12 Dec 2024
Completion
12 Dec 2024
Last update posted
24 Dec 2024
Registered enrollment
15
Registry id
NCT05500508

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.