Clinical trialNCT05509153RecruitingPhase 2Interventional

A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers

SponsorWestern Sydney Local Health DistrictEnrollment160Huntington Disease

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Carolyn Orr
Perron Institute
Principal Investigator
clinicaltrials.gov ↗
Clement Loy
University of Sydney
Principal Investigator
clinicaltrials.gov ↗
Dennis Velakoulis
Melbourne Health
Principal Investigator
clinicaltrials.gov ↗
John O'Sullivan
The University of Queensland
Principal Investigator
clinicaltrials.gov ↗
Rob Adam
The University of Queensland
Principal Investigator
clinicaltrials.gov ↗
Yenni Lie
Calvary Health Care Bethlehem
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Westmead Hospital
Westmead, New South Wales, Australia
Clement Loy
Recruiting
the University of Queensland
Herston, Queensland, Australia
John O'SullivanRob Adam
Not, yet, recruiting
Calvary Health Care Bethlehem
Parkdale, Victoria, Australia
Yenni Lie
Not, yet, recruiting
the Royal Melbourne Hospital
Parkville, Victoria, Australia
Dennis Velakoulis
Not, yet, recruiting
Perron Institute
Nedlands, Western Australia, Australia
Carolyn Orr
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jun 2024
Primary completion: 1 Nov 2026
Completion: 1 May 2027
Last update posted: 28 Feb 2025
Registered enrollment: 160
Registry id: NCT05509153

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.