Clinical trialNCT05550298RecruitingObservational

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

SponsorArkansas Children's Hospital Research InstituteEnrollment2,000Hematopoietic Cell TransplantRespiratory Viral InfectionSolid Organ Transplant

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT). Primary Objective To determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors. Secondary Objectives: * To develop and validate a classifier based on pre-transplant immunological profile predictive of developing an acute respiratory viral infection (aRVI), with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors. * To develop and validate a classifier based on Day +100 post-transplant immunological profiles predictive of developing an acute respiratory viral infection (aRVI),with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors .

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Gabriela Maron, MD
St. Jude Children's Research Hospital
Principal Investigator
clinicaltrials.gov ↗
William J. Steinbach, MD
Arkansas Children's Hospital Research Institute
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

27 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham'S (uab)
Birmingham, Alabama, United States
Maria Rueda Altez, MD
Recruiting
Arkansas Children'S Hospital
Little Rock, Arkansas, United States
Recruiting
Children'S National Medical
Washington D.C., District of Columbia, United States
Benjamin Hanisch, MD
Recruiting
University If Miami
Miami, Florida, United States
Ivan Gonzalez, MD
Recruiting
Emory and Children'S Healthcare of Atlanta
Atlanta, Georgia, United States
Kathryn Goggin, MD
Recruiting
University of Chicago Medicine Comer Children'S Hospital
Chicago, Illinois, United States
Madan Kumar
Recruiting
University of Louisville
Louisville, Kentucky, United States
Victoria Statler, MD
Recruiting
Boston Children'S Hospital
Boston, Massachusetts, United States
Recruiting
C.S. Mott Children'S Hospital
Ann Arbor, Michigan, United States
Jason Weinberg,, MD
Recruiting
Children'S Hospital of Michigan
Detroit, Michigan, United States
Arora Harbir, MD
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Beth Thielen, MD., PhD
Recruiting
Washington University
St Louis, Missouri, United States
Carol M Kao, MD
Recruiting
University of Nebraska Medical Center
Omaha, Nebraska, United States
Kari Neeman, MD
Recruiting
the Children'S Hospital at Montefiore
The Bronx, New York, United States
Marc Foca, MD
Recruiting
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Recruiting
Nationwide Children'S Hospital
Columbus, Ohio, United States
Masako Shimamura, MD
Recruiting
Upmc
Pittsburgh, Pennsylvania, United States
Recruiting
Medical University of South Carolina
Charleston, South Carolina, United States
Recruiting
Le Bonheur Children'S Hospital
Memphis, Tennessee, United States
Recruiting
St. Jude Children'S Research Hospital
Memphis, Tennessee, United States
Gabriela Maron, MDWilliam J Steinbach, MD
Recruiting
Ut Le Bonheur
Memphis, Tennessee, United States
Recruiting
Cook Children'S
Fort Worth, Texas, United States
Recruiting
Baylor College of Medicine
Houston, Texas, United States
Elizabeth Moulton, MD
Recruiting
Md Anderson Center Center
Houston, Texas, United States
Natalie D Garnes, MD
Recruiting
Uthealth Houston
Houston, Texas, United States
Ramia Zakhour, MD
Recruiting
Seattle Childrens
Seattle, Washington, United States
Recruiting
Children'S Hospital of Wisconsin
Milwaukee, Wisconsin, United States
Anna Huppler, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 13 Dec 2022
Primary completion: 31 Aug 2027
Completion: 31 Aug 2029
Last update posted: 2 Oct 2025
Registered enrollment: 2,000
Registry id: NCT05550298

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.