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Clinical trialNCT05574101Active, not recruitingPhase 2Interventional

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

SponsorMemorial Sloan Kettering Cancer CenterEnrollment34Cutaneous Squamous Cell CarcinomaLocally Advanced Cutaneous Squamous Cell CarcinomaLocally Advanced Skin Squamous Cell CarcinomaLocally Advanced Squamous Cell CarcinomaLocally Advanced Squamous Cell Carcinoma of the SkinSkin Cancer+1 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the study is to see if the combination of radiation therapy and cemiplimab immunotherapy is an effective treatment for people with locally advanced, unresectable CSCC.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Colorado (data Collection Only)

    Aurora, Colorado, United States

  • Moffitt Cancer Center (data Collection Only)

    Tampa, Florida, United States

  • Memorial Sloan Kettering Cancer Center at Basking Ridge (all Protocol Activities)

    Basking Ridge, New Jersey, United States

  • Memorial Sloan Kettering Monmouth (all Protocol Activities)

    Middletown, New Jersey, United States

  • Memorial Sloan Kettering Bergen (all Protocol Activities)

    Montvale, New Jersey, United States

  • Memorial Sloan Kettering Suffolk-Commack (all Protocol Activities)

    Commack, New York, United States

  • Memorial Sloan Kettering Westchester (all Protocol Activities)

    Harrison, New York, United States

  • Memorial Sloan Kettering Cancer Center (all Protocol Activities)

    New York, New York, United States

  • Memorial Sloan Kettering Nassau (all Protocol Activities)

    Rockville Centre, New York, United States

  • Cleveland Clinic (data Collection Only)

    Cleveland, Ohio, United States

  • Fox Chase Cancer Center (data Collection Only)

    Philadelphia, Pennsylvania, United States

  • Medical University of South Carolina

    Charleston, South Carolina, United States

  • University of Washington (data Collection Only)

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
6 Oct 2022
Primary completion
6 Oct 2026
Completion
6 Oct 2026
Last update posted
15 May 2026
Registered enrollment
34
Registry id
NCT05574101

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.