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Clinical trialNCT05610163Active, not recruitingPhase 2Interventional

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

SponsorAlliance for Clinical Trials in OncologyEnrollment783Locally Advanced Rectal CarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

685 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico
  • Cancer Center-Metro Medical Center Bayamon

    Bayamón, Puerto Rico

  • Doctors Cancer Center

    Manati, Puerto Rico

  • Centro Comprensivo de Cancer de Upr

    San Juan, Puerto Rico

  • Pan American Center for Oncology Trials Llc

    San Juan, Puerto Rico

  • San Juan City Hospital

    San Juan, Puerto Rico

  • San Juan Community Oncology Group

    San Juan, Puerto Rico

United States
  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, United States

  • University of South Alabama Mitchell Cancer Institute

    Mobile, Alabama, United States

  • Alaska Breast Care and Surgery Llc

    Anchorage, Alaska, United States

  • Alaska Oncology and Hematology Llc

    Anchorage, Alaska, United States

  • Alaska Women'S Cancer Care

    Anchorage, Alaska, United States

  • Anchorage Associates in Radiation Medicine

    Anchorage, Alaska, United States

  • Anchorage Oncology Centre

    Anchorage, Alaska, United States

  • Katmai Oncology Group

    Anchorage, Alaska, United States

  • Providence Alaska Medical Center

    Anchorage, Alaska, United States

  • Kingman Regional Medical Center

    Kingman, Arizona, United States

  • Cancer Center at Saint Joseph'S

    Phoenix, Arizona, United States

  • Mayo Clinic Hospital in Arizona

    Phoenix, Arizona, United States

  • Mercy Hospital Fort Smith

    Fort Smith, Arkansas, United States

  • Nea Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro

    Jonesboro, Arkansas, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, United States

  • Mission Hope Medical Oncology - Arroyo Grande

    Arroyo Grande, California, United States

  • Pcr Oncology

    Arroyo Grande, California, United States

  • Keck Medicine of Usc Buena Park

    Buena Park, California, United States

  • Providence Saint Joseph Medical Center/disney Family Cancer Center

    Burbank, California, United States

  • Mercy Cancer Center - Carmichael

    Carmichael, California, United States

  • Mercy San Juan Medical Center

    Carmichael, California, United States

  • City of Hope Comprehensive Cancer Center

    Duarte, California, United States

  • Mercy Cancer Center - Elk Grove

    Elk Grove, California, United States

  • Washington Hospital

    Fremont, California, United States

  • City of Hope at Irvine Lennar

    Irvine, California, United States

  • Uci Health - Chao Family Comprehensive Cancer Center and Ambulatory Care

    Irvine, California, United States

  • Los Angeles General Medical Center

    Los Angeles, California, United States

  • Usc / Norris Comprehensive Cancer Center

    Los Angeles, California, United States

  • Mercy Cancer Center

    Merced, California, United States

  • Providence Queen of the Valley

    Napa, California, United States

  • Usc Norris Oncology/hematology-Newport Beach

    Newport Beach, California, United States

  • Saint Joseph Hospital - Orange

    Orange, California, United States

  • Uc Irvine Health/chao Family Comprehensive Cancer Center

    Orange, California, United States

  • Mercy Cancer Center - Rocklin

    Rocklin, California, United States

645 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
8 Dec 2022
Primary completion
30 Sept 2026
Completion
30 Sept 2033
Last update posted
8 Sept 2025
Registered enrollment
783
Registry id
NCT05610163

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.