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Clinical trialNCT05626634CompletedPhase 2Interventional

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

SponsorLongboard PharmaceuticalsEnrollment41Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objective of this study is to assess the long-term safety, tolerability, and efficacy of adjunctive therapy of LP352 in subjects with developmental and epileptic encephalopathies who completed participation in Study LP352-201.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

28 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Queensland Children'S Hospital

    South Brisbane, Queensland, Australia

  • Austin Health

    Heidelberg, Victoria, Australia

  • Alfred Health

    Melbourne, Victoria, Australia

United States
  • Arkansas Children'S Hospital

    Little Rock, Arkansas, United States

  • Rancho Los Amigos National Rehabilitation Center (rlanrc)

    Downey, California, United States

  • University of California San Francisco

    San Francisco, California, United States

  • Northwest Florida Clinical Research Group

    Gulf Breeze, Florida, United States

  • University of Miami

    Miami, Florida, United States

  • Advent Health Orlando

    Orlando, Florida, United States

  • Research Institute of Orlando

    Orlando, Florida, United States

  • University of South Florida

    Tampa, Florida, United States

  • Hawaii Pacific Neuroscience

    Honolulu, Hawaii, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, United States

  • Mid-Atlantic Epilepsy and Sleep Center

    Bethesda, Maryland, United States

  • Spectrum Health

    Grand Rapids, Michigan, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Boston Children'S Health Physicians Llp

    Hawthorne, New York, United States

  • Northwell Health

    New York, New York, United States

  • Northeast Regional Epilepsy Group

    Staten Island, New York, United States

  • Onsite Clinical Solutions Llc

    Charlotte, North Carolina, United States

  • Wake Forest University School of Medicine

    Winston-Salem, North Carolina, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, United States

  • Providence Neurological Specialties-East

    Portland, Oregon, United States

  • Austin Epilepsy Care Center

    Austin, Texas, United States

  • Child Neurology Consultants of Austin

    Austin, Texas, United States

  • University of Utah

    Salt Lake City, Utah, United States

  • University of Washington Valley Medical Center

    Renton, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

LP352, bexicaserin
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
8 Nov 2022
Primary completion
20 Dec 2024
Completion
20 Dec 2024
Last update posted
3 Dec 2025
Registered enrollment
41
Registry id
NCT05626634

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.