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Clinical trialNCT05658913RecruitingObservational

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

SponsorUniversity of PennsylvaniaEnrollment100Alzheimer's Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To collect Tau PET/CT imaging in older adults diagnosed with Mild Cognitive Impairment (MCI) or Alzheimer's Disease (AD) in the Mismatch Prospective Cohort Study (MPC-Tau) study to determine relationship to clinical, cognitive, and other biomarker data. Findings from this study will likely provide insight into the phenotypic variability of Alzheimer's Disease and other related pathologies.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

  • David A. Wolk

    University of Pennsylvania Department of Neurology at the Perelman School of Medicine

    Principal Investigator
  • Sandhitsu R. Das

    University of Pennsylvania Department of Neurology at the Perelman School of Medicine

    Principal Investigator

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Massachusetts General Hospital

    Boston, Massachusetts, United States

    Bradford Dickerson, MD
    Recruiting
  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

    David Wolk, MDSandhitsu Das, PhD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AV-1451
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
14 Mar 2023
Primary completion
31 Dec 2027
Completion
31 Dec 2029
Last update posted
5 Sept 2025
Registered enrollment
100
Registry id
NCT05658913

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.