Clinical trialNCT05691478RecruitingPhase 2/PHASE3Interventional

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

SponsorNational Cancer Institute (NCI)Enrollment1,122High Grade OsteosarcomaLocalized OsteosarcomaMetastatic OsteosarcomaSecondary Osteosarcoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Michael W Bishop
Children's Oncology Group
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

198 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Sydney Children'S Hospital
Randwick, New South Wales, Australia
Draga Barbaric
Recruiting
the Children'S Hospital at Westmead
Westmead, New South Wales, Australia
Bhavna Padhye
Recruiting
Queensland Children'S Hospital
South Brisbane, Queensland, Australia
Steven A. Foresto
Recruiting
Women'S and Children'S Hospital-Adelaide
North Adelaide, South Australia, Australia
Maria L. Kirby
Recruiting
Monash Medical Center-Clayton Campus
Clayton, Victoria, Australia
Michelle Martin
Recruiting
Royal Children'S Hospital
Parkville, Victoria, Australia
Martin A. Campbell
Recruiting
Perth Children'S Hospital
Perth, Western Australia, Australia
Michelle Ng
Recruiting

Canada

Alberta Children'S Hospital
Calgary, Alberta, Canada
Victor A. Lewis
Recruiting
University of Alberta Hospital
Edmonton, Alberta, Canada
Sarah J. McKillop
Recruiting
Cancercare Manitoba
Winnipeg, Manitoba, Canada
Stephanie M. Villeneuve
Recruiting
Iwk Health Centre
Halifax, Nova Scotia, Canada
Chelsea Ash
Recruiting
Children'S Hospital
London, Ontario, Canada
Shayna M. Zelcer
Recruiting
Children'S Hospital of Eastern Ontario
Ottawa, Ontario, Canada
Donna L. Johnston
Recruiting
Hospital for Sick Children
Toronto, Ontario, Canada
Sarah A. Cohen-Gogo
Recruiting
Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, Canada
Monia Marzouki
Recruiting
the Montreal Children'S Hospital of the Muhc
Montreal, Quebec, Canada
Stephanie Mourad
Recruiting
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Sherbrooke, Quebec, Canada
Josee Brossard
Recruiting
Jim Pattison Children'S Hospital
Saskatoon, Saskatchewan, Canada
Kathleen Felton
Recruiting
Chu de Quebec-Centre Hospitalier de L'Universite Laval (chul)
Québec, Canada
Bruno Michon
Recruiting

New Zealand

Starship Children'S Hospital
Grafton, Auckland, New Zealand
Mandy PohLui de Silva
Recruiting
Christchurch Hospital
Christchurch, New Zealand
Tristan Pettit
Recruiting

United States

Children'S Hospital of Alabama
Birmingham, Alabama, United States
Jamie M. Aye
Recruiting
Banner Children'S at Desert
Mesa, Arizona, United States
Joseph C. Torkildson
Recruiting
Mayo Clinic Hospital in Arizona
Phoenix, Arizona, United States
Wendy Allen-Rhoades
Recruiting
Phoenix Childrens Hospital
Phoenix, Arizona, United States
Alok K. Kothari
Recruiting
Banner University Medical Center - Tucson
Tucson, Arizona, United States
Monica M. Davini
Recruiting
Arkansas Children'S Hospital
Little Rock, Arkansas, United States
Michael W. Bishop
Recruiting
Kaiser Permanente Downey Medical Center
Downey, California, United States
Robert M. Cooper
Recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Janet M. Yoon
Recruiting
Loma Linda University Medical Center
Loma Linda, California, United States
Albert Kheradpour
Recruiting
Miller Children'S and Women'S Hospital Long Beach
Long Beach, California, United States
Jacqueline N. Casillas
Recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Leo Mascarenhas
Recruiting
Children'S Hospital Los Angeles
Los Angeles, California, United States
Fariba Navid
Recruiting
Mattel Children'S Hospital Ucla
Los Angeles, California, United States
Suspended
Valley Children'S Hospital
Madera, California, United States
Ruetima Titapiwatanakun
Recruiting
Kaiser Permanente-Oakland
Oakland, California, United States
Aarati V. Rao
Recruiting
Ucsf Benioff Children'S Hospital Oakland
Oakland, California, United States
Jennifer G. Michlitsch
Recruiting
Children'S Hospital of Orange County
Orange, California, United States
Elyssa M. Rubin
Recruiting
Lucile Packard Children'S Hospital Stanford University
Palo Alto, California, United States
Jay Michael S. Balagtas
Recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Marcio H. Malogolowkin
Recruiting

158 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 3 Mar 2023
Primary completion: 20 Mar 2030
Completion: 20 Mar 2030
Last update posted: 8 Jul 2026
Registered enrollment: 1,122
Registry id: NCT05691478

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.