Clinical trialNCT05753813RecruitingEarly phase 1Interventional

Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome

SponsorQueen's Medical CenterEnrollment22Bacterial VaginosisVulvovaginal Candidiasis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This project aims to investigate if the contraceptive method, Phexxi, causes changes to the composition of the vaginal microbiome. The investigators hypothesize that regular use of Phexxi will cause increased colonization of lactic acid-producing lactobacilli, which could have positive effects in the way of preventing recurrent episodes of BV and candida infections.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Bliss Kaneshiro, MD, MPH
Queen's Medical Center
Principal Investigator
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Corrie Miller, DO
University of Hawaii
Principal Investigator
clinicaltrials.gov ↗
Olivia Manayan, MD, MPH
University of Hawaii
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Queens Medical Center, 1004 Clinic Pob1
Honolulu, Hawaii, United States
Olivia H Manayan, MD MPH
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Phexxi

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Dec 2023
Primary completion: 30 Oct 2026
Completion: 30 Dec 2026
Last update posted: 20 Feb 2026
Registered enrollment: 22
Registry id: NCT05753813

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.