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Clinical trialNCT05757219RecruitingPhase 2Interventional

Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

SponsorH. Lee Moffitt Cancer Center and Research InstituteEnrollment27Diffuse Large B Cell Lymphoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the study is to assess the safety and efficacy of once daily itacitinib oral administration in participants with diffuse large B-cell lymphoma (DLBCL) who will receive CAR-T cell therapy with axicabtagene ciloleucel (axi-cel).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Moffitt Cancer Center

    Tampa, Florida, United States

    Aleksandr Lazaryan, MD, MPH, PhDBijal Shah, MD, MSFarhad Khimani, MDFrederick Locke, MDHien Liu, MDJavier Pinilla, MD, PhDJulio Chavez, MD, MSMichael Jain, MD, PhDRawan Faramand, MDTaiga Nishihori, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Chimeric antigen receptor T-cellsItacitinib
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
19 May 2023
Primary completion
20 Jun 2026
Completion
31 Jan 2027
Last update posted
31 Mar 2026
Registered enrollment
27
Registry id
NCT05757219
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.