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Clinical trialNCT05781321Active, not recruitingPhase 2Interventional

Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study

SponsorMayo ClinicEnrollment170Glioblastoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial compares the effect of short course radiotherapy (RT) to standard course RT for the treatment of patients diagnosed with glioblastoma (GBM). The researchers want to learn whether the shorter course treatment is non-inferior (not worse than the standard of care), for patients with GBM. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Short course radiotherapy delivers higher doses of radiation over a shorter period of time and may kill more tumor cells and have fewer side effects.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Mayo Clinic in Arizona

    Scottsdale, Arizona, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, United States

  • Mayo Clinic Health System in Albert Lea

    Albert Lea, Minnesota, United States

  • Mayo Clinic Health Systems-Mankato

    Mankato, Minnesota, United States

  • Mayo Clinic Radiation Therapy - Northfield

    Northfield, Minnesota, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, United States

  • Mayo Clinic Health System-Eau Claire

    Eau Claire, Wisconsin, United States

  • Mayo Clinic Health System-Franciscan Healthcare

    La Crosse, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

FluorodopaTemozolomide →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
23 Mar 2023
Primary completion
30 Nov 2026
Completion
30 Nov 2028
Last update posted
30 Jul 2026
Registered enrollment
170
Registry id
NCT05781321
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.