Clinical trialNCT05804318RecruitingInterventional

Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

SponsorVarian, a Siemens Healthineers CompanyEnrollment132Prostate Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This trial is a prospective, single-arm, multi-center clinical trial designed to assess whether adaptive radiotherapy with urethral sparing for low to intermediate risk localized prostate cancer will translate into a decreased rate of patient reported acute urinary side effects, as measured by the patient reported EPIC-26 questionnaire, compared with the historically reported rate for non-adaptive, non-urethral sparing prostate SBRT.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jeremy Bredfeldt, PhD
Brigham and Women's Hospital
Principal Investigator
clinicaltrials.gov ↗
Jonathan Leeman, MD
Brigham and Women's Hospital
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Germany

Klinikum Der Landeshauptstadt Stuttgart Gkaör
Stuttgart, Baden-Wurttemberg, Germany
Marc Münter, MD
Recruiting
Universitätsklinikum Des Saarlandes (saarland Univerisity Hospital)
Homburg, Saarland, Germany
Markus Hecht, MD
Recruiting

Spain

Hospital Universitario de Navarra
Pamplona, Navarre, Spain
Marta Barrado Los Arcos, MD
Recruiting

United States

Duarte Cancer Center
Duarte, California, United States
Percy Lee, MD
Recruiting
City of Hope Orange County Lennar Foundation Cancer Center
Irvine, California, United States
Percy Lee, MD
Recruiting
Brigham and Women'S Hospital
Boston, Massachusetts, United States
Active, not recruiting
Washington University in St. Louis
St Louis, Missouri, United States
James Randall, MD
Recruiting
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States
Active, not recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 13 Apr 2023
Primary completion: 31 Jul 2026
Completion: 31 Jul 2031
Last update posted: 28 May 2026
Registered enrollment: 132
Registry id: NCT05804318

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.