findmyKOL
Clinical trialNCT05826353CompletedPhase 3Interventional

A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

SponsorKowa Research Institute, Inc.Enrollment110Fuchs Endothelial Corneal Dystrophy
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

A study to assess the safety and efficacy of K-321 in participants with FECD after simultaneous cataract surgery and descemetorhexis.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

43 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Dr. Greg Moloney

    Vancouver, British Columbia, Canada

  • Prism Eye Institute - Mississauga-Oakville

    Oakville, Ontario, Canada

  • Precision Cornea Centre

    Ottawa, Ontario, Canada

Denmark
  • Rigshospitalet Glostrup-Valdemar Hansens Vej 1-23

    Glostrup Municipality, Capital, Denmark

  • Aarhus Universitetshospital

    Aarhus N, Central Jutland, Denmark

Germany
  • Universitätsklinikum Heidelberg

    Heidelberg, Baden-Wurttemberg, Germany

  • Universitätsklinikum Tübingen

    Tübingen, Baden-Wurttemberg, Germany

  • Universitatsklinkum Erlangen-Ulmenweg 18

    Erlangen, Bavaria, Germany

  • Uniklinik Köln

    Cologne, North Rhine-Westphalia, Germany

  • Universitatsklinikum Dusseldorf

    Düsseldorf, North Rhine-Westphalia, Germany

  • Universität Des Saarlandes

    Homburg, Saarland, Germany

  • Lmu Klinikum Der Universität

    München, Germany

Spain
  • Hospital Universitario Germans Trias I Pujol

    Badalona, Barcelona, Spain

  • Althaia Xarxa Assistencial Universitaria Manresa

    Manresa, Barcelona, Spain

  • Hospital Arruzafa

    Córdoba, Córdoba, Spain

  • Instituto Oftalmologico Fernandez Vega

    Oviedo, Principality of Asturias, Spain

  • Institut Catala de Retina (icr)

    Barcelona, Spain

  • Instituto de Microcirugia Ocular

    Barcelona, Spain

  • Oftalvist - Barcelona

    Barcelona, Spain

United Kingdom
  • the Royal Liverpool University Hospital

    Liverpool, Lancashire, United Kingdom

  • Moorfields Eye Hospital

    London, London, City of, United Kingdom

  • Royal Victoria Infirmary

    Newcastle upon Tyne, Tyne and Wear, United Kingdom

United States
  • Keck Hospital of Usc

    Los Angeles, California, United States

  • Macy Eye Center

    Los Angeles, California, United States

  • Byers Eye Institute at Stanford

    Palo Alto, California, United States

  • Sacramento Eye Consultants

    Sacramento, California, United States

  • Gorovoy Md Eye Specialists

    Fort Myers, Florida, United States

  • Bascom Palmer Eye Institute

    Palm Beach Gardens, Florida, United States

  • Grene Vision Group-Wichita

    Wichita, Kansas, United States

  • University of Kentucky

    Lexington, Kentucky, United States

  • W Kellogg Eye Center

    Ann Arbor, Michigan, United States

  • Verdier Eye Center

    Grand Rapids, Michigan, United States

  • Vance Thompson Vision - Omaha

    Omaha, Nebraska, United States

  • Eye Associates of New Mexico - Albuquerque - Northside

    Albuquerque, New Mexico, United States

  • Nyu Langone Health

    New York, New York, United States

  • Vance Thompson Vision West Fargo

    West Fargo, North Dakota, United States

  • Cincinnati Eye Institute-1945 Cei Dr

    Blue Ash, Ohio, United States

  • University Hospitals Cleveland Medical Center - 11100 Euclid Ave

    Cleveland, Ohio, United States

  • Devers Eye Institute

    Portland, Oregon, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, United States

3 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboRipasudil
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
11 May 2023
Primary completion
17 Jan 2025
Completion
24 Oct 2025
Last update posted
22 Jan 2026
Registered enrollment
110
Registry id
NCT05826353

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.