Clinical trialNCT05828823RecruitingInterventional

Incremental Hemodialysis: The TwoPlus Trial

SponsorWake Forest University Health SciencesEnrollment350End-Stage Kidney Disease

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Mariana Murea, MD
Wake Forest Health Sciences
Principal Investigator
clinicaltrials.gov ↗
Peter Kotanko
Renal Research Institute
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Florida
Jacksonville, Florida, United States
Alaa Awad
Recruiting
Emory University
Atlanta, Georgia, United States
Vandana Dua Niyyar
Recruiting
Johns Hopkins University School of Medicine (jhusm)
Baltimore, Maryland, United States
Gautam Samir, MD
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Sagar Nigwekar
Recruiting
University of Mississippi Medical Center
Jackson, Mississippi, United States
Neville Dossabhoy, MD
Recruiting
Renal Research Institute (rri)
New York, New York, United States
Rasha Hussein, MD
Recruiting
Northwell Health
Queens, New York, United States
Steven Fishbane
Recruiting
University of North Carolina Chapel Hill
Chapel Hill, North Carolina, United States
Jennifer Flythe, MD
Recruiting
Atrium Health Wake Forest Baptist
Winston-Salem, North Carolina, United States
Mariana Murea, MD
Recruiting
University of Virginia (uva)
Charlottesville, Virginia, United States
Emaad Abdel-Rahman, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 26 Feb 2024
Primary completion: 31 Jul 2030
Completion: 31 Jan 2031
Last update posted: 22 May 2026
Registered enrollment: 350
Registry id: NCT05828823

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.