FindMyKOL
Clinical trialNCT05839379RecruitingObservational

Targeted Pediatric High-Grade Glioma Therapy

SponsorNationwide Children's HospitalEnrollment350Anaplastic AstrocytomaDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantGlioblastomaGlioblastoma MultiformeHigh Grade Glioma+3 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent treatment-based clinical trial based on the genetic alterations identified in their tumor.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

21 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Sydney Children'S Hospital

    Randwick, New South Wales, Australia

    Recruiting
  • Queensland Children'S Hospital

    South Brisbane, Queensland, Australia

    Recruiting
  • Royal Children'S Hospital

    Melbourne, Victoria, Australia

    Recruiting
  • Perth Children'S Hospital

    Perth, Western Australia, Australia

    Recruiting
Canada
  • the Hospital for Sick Children (sickkids)

    Toronto, Ontario, Canada

    Not, yet, recruiting
  • Montreal Children'S Hospital

    Montreal, Quebec, Canada

    Not, yet, recruiting
Germany
  • Hopp Children'S Cancer Center at Nct Heidelberg (kitz)

    Heidelberg, Baden-Wurttemberg, Germany

    Not, yet, recruiting
Netherlands
  • Princess Máxima Center

    Utrecht, Netherlands

    Not, yet, recruiting
New Zealand
  • Starship Children'S Hospital

    Auckland, Grafton, New Zealand

    Not, yet, recruiting
United Kingdom
  • Great Ormond Street Hospital

    London, United Kingdom

    Not, yet, recruiting
United States
  • Children'S Hospital Colorado

    Aurora, Colorado, United States

    Not, yet, recruiting
  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

    Recruiting
  • Ann & Robert H. Lurie Children'S Hospital of Chicago

    Chicago, Illinois, United States

    Recruiting
  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

    Not, yet, recruiting
  • C.S. Mott Children'S Hospital

    Ann Arbor, Michigan, United States

    Recruiting
  • Duke University Health System

    Durham, North Carolina, United States

    Recruiting
  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

    Recruiting
  • Nationwide Children'S Hospital

    Columbus, Ohio, United States

    Recruiting
  • Children'S Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States

    Not, yet, recruiting
  • Texas Children'S Hospital

    Houston, Texas, United States

    Recruiting
  • Seattle Children'S Hospital

    Seattle, Washington, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
2 Aug 2024
Primary completion
28 Aug 2029
Completion
28 Aug 2034
Last update posted
10 Jun 2026
Registered enrollment
350
Registry id
NCT05839379

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.