The Role of Red Flavonoid in Photoaging

The goal of this clinical trial is to learn about the effects of "red flavonoid" substance on skin, which is extracted from a plant called Camellia japonica, in adults aged of 45 or older with photo-damaged skin. The main questions it aims to answer are: * Does red flavonoid have an anti-aging effect? * Does red flavonoid have any skin quality-improving effects? Participants will * Be using creams with or without red flavonoid (only moisturizing creams) and sun-screen for the duration of the study. * Get a skin biopsy before and after using the creams. * Be taken photos of the face and neck region and have a skin examination at each visit. * Complete a self-questionnaire at final visit. Researchers will compare the group who uses red flavonoid facial cream with the group who uses moisturizing cream to see if red flavonoid has an effect on appearance and structure.