Clinical trialNCT05889624RecruitingInterventional

Responding With Evidence and Access for Childhood Headaches

SponsorChildren's Hospital Medical Center, CincinnatiEnrollment400Chronic MigraineHeadacheHeadache DisordersHeadache, MigraineMigraineMigraine Disorders+2 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the feasibility of Cognitive Behavioral Therapy (CBT) via telehealth for youth with migraine. The focus is on applying evidence-based care and enhancing access to it. CBT via telehealth while taking a clinically-prescribed, pill-based prevention therapy (amitriptyline) will be compared to CBT via telehealth alone.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Scott Powers, PhD
Cincinnati Childrens Medical Center, Cincinnati
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham Children'S of Alabama
Birmingham, Alabama, United States
Scott Turner, DNP
Recruiting
Phoenix Children'S Hospital - Barrow Neurological Institute
Phoenix, Arizona, United States
Reena Rastogi, Md
Recruiting
University of California San Francisco
San Francisco, California, United States
Hannah Shapiro, MD
Recruiting
University of Colorado/children'S Hospital Colorado
Aurora, Colorado, United States
Marcy Yonker, MD
Recruiting
Nemours Children'S Health System
Wilmington, Delaware, United States
Judy Adelizzi-Delany, DNP
Recruiting
Clinical Integrative Research Center of Atlanta, Inc
Atlanta, Georgia, United States
Chaouki Khoury, MDFrank Berenson, MD
Recruiting
Norton Children'S Neuroscience Institute/ Uofl School of Medicine
Louisville, Kentucky, United States
Elizabeth Doll, MD
Recruiting
Louisiana State Univ/children'S Hospital of New Orleans
New Orleans, Louisiana, United States
Rashmi Rao, MD
Recruiting
Dent Neurological Institute
Amherst, New York, United States
Jennifer McVige, MD
Recruiting
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Joanne Kacperski, MD
Recruiting
Nationwide Childrens
Columbus, Ohio, United States
Ann Pakalnis, MD
Recruiting
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Christina Szperka, MD
Recruiting
University of Tennessee Health Science Center/ Lebonheur Children'S Hospital
Memphis, Tennessee, United States
Ankita Gosh, MD
Recruiting
Dell Children'S Hospital-Ut Health
Austin, Texas, United States
Sara Pavitt, MD
Recruiting
Marshall Health
Huntington, West Virginia, United States
Ivan Lopez, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Amitriptyline →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 22 Aug 2023
Primary completion: 31 Jul 2027
Completion: 31 Dec 2027
Last update posted: 10 Aug 2026
Registered enrollment: 400
Registry id: NCT05889624

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.