Clinical trialNCT05916469RecruitingObservational

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

SponsorOregon Health and Science UniversityEnrollment300Bleeding DisorderHeavy Menstrual BleedingVon Willebrand Diseases

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this multicenter prospective observational study and registry of U.S. adolescents and young adults with heritable bleeding disorders is to determine the bleeding outcomes, satisfaction, hemostatic parameter changes, and patient reported quality of life after 6 months of use of either of two commonly used hormonal treatments for menstrual suppression - levonorgestrel intrauterine device (LNG-IUD) and norethindrone acetate (NETA). Under this application the study will compare the two treatments and compare outcomes after LNG-IUD treatment results to a control group without a bleeding disorder, with the goal of determining the benefits and expected outcomes of these treatment options for this population.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Allison Wheeler
University of Washington
Principal Investigator
clinicaltrials.gov ↗
Maureen Baldwin, MD MPH
Oregon Health and Science University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Stanford
Palo Alto, California, United States
Not, yet, recruiting
Colorado Anschutz Medical Campus
Aurora, Colorado, United States
Not, yet, recruiting
Emory
Atlanta, Georgia, United States
Not, yet, recruiting
University of Michigan Medicine
Ann Arbor, Michigan, United States
Not, yet, recruiting
Children'S Mercy
Kansas City, Missouri, United States
Not, yet, recruiting
Oregon Health & Science University
Portland, Oregon, United States
Recruiting
Penn State Health
Hershey, Pennsylvania, United States
Not, yet, recruiting
Seattle Children'S Hospital
Seattle, Washington, United States
Not, yet, recruiting
University of Washington
Seattle, Washington, United States
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Levonorgestrel →Norethindrone →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 24 Sept 2025
Primary completion: 31 Dec 2028
Completion: 30 Jun 2029
Last update posted: 17 Dec 2025
Registered enrollment: 300
Registry id: NCT05916469

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.