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Clinical trialNCT05918575RecruitingInterventional

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

SponsorRush University Medical CenterEnrollment250Extubation FailureObesity, Morbid
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Around 20% of the obese patients with higher body mass index (BMI) who are taken off the breathing tube and breathing machine (ventilator) end up needing it back to support breathing. The re-application of breathing tube is associated with poor outcomes, including high risk of pneumonia, longer hospital stays, and death. The purpose of this study is to assess if prophylactic use of noninvasive breathing support after removing the breathing tube lowers the chance of needing the breathing tube again.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Mexico
  • Hospital Civil Fray Antonio Alcalde

    Guadalajara, Jalisco, Mexico

    Miguel Ángel Ibarra Estrada, MD
    Recruiting
United States
  • Rush University Medical Center

    Chicago, Illinois, United States

    Babak Mokhlesi, MDRamandeep Kaur, PhD
    Recruiting
  • Central Dupage Hospital

    Winfield, Illinois, United States

    Ankeet Patel
    Not, yet, recruiting
  • Mcgovern Medical School, the University of Texas Health Science Center

    Houston, Texas, United States

    Rosa M. Estrada-Y-Martin, MD
    Recruiting
  • Medical College of Wisconsin

    Milwaukee, Wisconsin, United States

    Rahul Nanchal, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
10 Jul 2023
Primary completion
1 Jul 2028
Completion
1 Dec 2028
Last update posted
7 Aug 2026
Registered enrollment
250
Registry id
NCT05918575
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.