Clinical trialNCT05934487RecruitingInterventional

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

SponsorEndotronix, Inc.Enrollment1,750Heart FailureHeart Failure NYHA Class IIHeart Failure NYHA Class III

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Edward Karst
Edwards Lifesciences IHFM
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

48 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium

Azorg Aalst
Aalst, Belgium
Active, not recruiting
Uz Brussel
Brussels, Belgium
Active, not recruiting

Ireland

University Hospital Galway
Galway, Ireland
Active, not recruiting

United States

St. Joseph'S Hospital and Medical Center
Phoenix, Arizona, United States
Namit Rohant
Recruiting
Usc
Los Angeles, California, United States
Aaron Wolfson
Recruiting
Ucsf Medical Center
San Francisco, California, United States
Shweta Motiwala, MD
Recruiting
Baptist Health South Florida
Miami, Florida, United States
Sandra Chaparro, MD
Recruiting
Ascension Sacred Heart
Pensacola, Florida, United States
Rohit Amin
Recruiting
Piedmont
Atlanta, Georgia, United States
Kent Nilsson
Recruiting
Advocate Health System
Downers Grove, Illinois, United States
Ali Valika
Recruiting
Heart Care Centers of Illinois (hcci)
Palos Park, Illinois, United States
Chirag Rajyaguru
Recruiting
Ascension St. Vincent'S
Indianapolis, Indiana, United States
Ashwin Ravichandran
Recruiting
University of Kansas Medical Center (kumc)
Kansas City, Kansas, United States
Hirak Shah, MD
Recruiting
Medstar
Baltimore, Maryland, United States
Erika Feller
Recruiting
Boston Medical Center Corporation
Boston, Massachusetts, United States
Nir Ayalon, MD
Not, yet, recruiting
Tufts Medical Center
Boston, Massachusetts, United States
Michael Kiernan, MD
Recruiting
Ascension Providence Hospital Cardiology - Heart Cardiology
Howell, Michigan, United States
Marcel Zughaib, MD
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Tamas Alexy, MD
Recruiting
Centra Care Heart Center
Saint Cloud, Minnesota, United States
Jamie Pelzel, MD
Recruiting
St. Lukes/ Mid-American Heart Institute
Kansas City, Missouri, United States
Michael Nassif, MD
Recruiting
Lenox Hill/ Northwell Health
New York, New York, United States
Sirish Vullaganti, MD
Recruiting
Mount Sinai
New York, New York, United States
Noah Moss, MD
Recruiting
Mount Sinai West
New York, New York, United States
Johanna Contreras, MD
Recruiting
Stony Brook University Med Center
Stony Brook, New York, United States
Hal Skopicki, MD
Recruiting
Duke University
Durham, North Carolina, United States
Marat Fudim, MD
Recruiting
Unc Medical Center
Durham, North Carolina, United States
William Mostertz, MD
Recruiting
the Christ Hospital- Cincinnati
Cincinnati, Ohio, United States
Ankit Bhatia, MD
Recruiting
University of Cincinnati
Cincinnati, Ohio, United States
Vlad Cotarlan, MD
Recruiting
University Hospital (cleveland)
Cleveland, Ohio, United States
Monique Robinson, MD
Recruiting
Oregon Health Science Portland
Portland, Oregon, United States
Luke Masha, MD
Recruiting
Providence St. Vincent'S - Portland
Portland, Oregon, United States
Christopher Chien
Recruiting
Penn State Health
Hershey, Pennsylvania, United States
John Boehmer, MD
Recruiting
Upmc
Pittsburgh, Pennsylvania, United States
Gavin Hickey, MD
Recruiting
Medical University of South Carolina (musc)
Charleston, South Carolina, United States
Vishal Rao
Recruiting
Prisma Health- Upstate
Greenville, South Carolina, United States
Jason Guichard, MD
Recruiting
Sanford
Sioux Falls, South Dakota, United States
Marian Petrasko, MD
Recruiting
Vanderbilt
Nashville, Tennessee, United States
Sandip Zalawadiya, MD
Recruiting
Austin Heart
Austin, Texas, United States
Faisal Syed, MD
Recruiting
Baylor Scott & White -Dallas
Dallas, Texas, United States
Cesar Guerrero, MD
Recruiting
Medical City Healthcare Dallas
Dallas, Texas, United States
Claudius Mahr, MD
Recruiting

8 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 29 Nov 2023
Primary completion: 30 Sept 2028
Completion: 30 Sept 2033
Last update posted: 29 Jun 2026
Registered enrollment: 1,750
Registry id: NCT05934487

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.