Clinical trialNCT05954858RecruitingInterventional

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

SponsorNorthwell HealthEnrollment32Brain CancerGBMGlioblastomaGlioblastoma MultiformeGlioblastoma Multiforme, AdultGlioma, Malignant+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This single center, single arm, open-label, phase 2 study will assess the safety and efficacy of a pedicled temporoparietal fascial (TPF) or pericranial flap into the resection cavity of newly diagnosed glioblastoma multifome (GBM) patients. The objective of the Phase 2 study is to demonstrate that this surgical technique is safe and effective in a human cohort of patients with resected newly diagnosed AA or GBM and may improve progression-free survival (PFS) and overall survival (OS).

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

John Boockvar, MD
Feinstein Institute for Medical Research/Lenox Hill Hospital
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Lenox Hill Brain Tumor Center
New York, New York, United States
Amy McKewon, NPAvraham Zlochower, MDDavid Langer, MDDeborah Gruber, MDNetanel Ben-Shalom, MDOlivia Albers, NPRandy D'Amico, MDTamika Wong, MPHVadim Zhigin, PA
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 29 Jun 2023
Primary completion: 30 Jun 2028
Completion: 30 Jun 2029
Last update posted: 1 Jun 2026
Registered enrollment: 32
Registry id: NCT05954858

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.