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Clinical trialNCT05956821RecruitingPhase 1/PHASE2Interventional

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

SponsorUniversity of MiamiEnrollment20Anaplastic AstrocytomaDIPG Brain TumorDiffuse Intrinsic Brainstem GliomaDiffuse Intrinsic Pontine GliomaFibrillary AstrocytomasGlioblastoma Multiforme+2 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study assesses the safety and efficacy of repeat monthly dosing of super-selective intra-arterial cerebral infusion (SIACI) of cetuximab and bevacizumab in patients \< 22 years of age.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Jackson Memorial Hospital

    Miami, Florida, United States

    Heather McCrea, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

SIACI of cetuximab and bevacizumab
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
19 Jun 2025
Primary completion
1 Oct 2029
Completion
1 Dec 2029
Last update posted
8 Dec 2025
Registered enrollment
20
Registry id
NCT05956821
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.