Clinical trialNCT05966038RecruitingObservational

ALS/MND Natural History Study Data Repository

SponsorMassachusetts General HospitalEnrollment5,000ALSKennedy DiseaseMND (Motor Neurone DIsease)PBP - Progressive Bulbar PalsyPLSPMA - Progressive Muscular Atrophy

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alexander Sherman
Massachusetts General Hospital
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

18 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Israel

Hadassah Medical Organization
Jerusalem, Israel
Marc Gotkine, MD
Recruiting
Tel Aviv Medical Center
Tel Aviv, Israel
Vivian Drori, MD
Recruiting

Italy

Centro Clinico Nemo Milano
Milan, Italy
Federica Cerri
Recruiting
Istituti Clinici Scientifici Maugeri Spa
Milan, Italy
Christian Lunetta, MDRachele Piras, MD
Recruiting

United States

Loma Linda University Health
Loma Linda, California, United States
Jeffrey Rosenfeld, MD
Recruiting
Kaiser Permanente
Los Angeles, California, United States
Abel Wu, MD
Recruiting
University of Florida
Gainesville, Florida, United States
James Wymer
Recruiting
Northwestern University
Chicago, Illinois, United States
Senda Ajroud-Driss
Recruiting
Lahey Clinic
Burlington, Massachusetts, United States
Medhi Ghasemi, MD
Recruiting
Henry Ford Health System
Detroit, Michigan, United States
Ximena Arcila Londono
Recruiting
Trinity Health Michigan
Grand Rapids, Michigan, United States
Melanie G Taylor, MD
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
David Walk
Recruiting
Saint Louis University
St Louis, Missouri, United States
Ghazala Hayat
Recruiting
Providence Als Clinic
Portland, Oregon, United States
Nicholas Olney
Recruiting
Temple University Lewis Katz School of Medicine
Philadelphia, Pennsylvania, United States
Terry Heiman-Patterson
Recruiting
Thomas Jefferson University
Philadelphia, Pennsylvania, United States
Hristelina Ilieva, MD
Recruiting
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
Tawfiq Al-lahham, MD
Recruiting
Virginia Commonwealth University
Richmond, Virginia, United States
Kelly Gwathmey
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Apr 2015
Primary completion: 31 Dec 2030
Completion: 31 Dec 2030
Last update posted: 20 May 2026
Registered enrollment: 5,000
Registry id: NCT05966038

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.