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Clinical trialNCT05984927Active, not recruitingPhase 1/PHASE2Interventional

NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration

SponsorElisigen, Inc.Enrollment20Age-Related Macular Degeneration
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will evaluate the safety, tolerability, and preliminary efficacy of NG101 AAV gene therapy administered by subretinal injections into a single selected eye as a single selected dose for patients with wet age-related macular degeneration (wAMD).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Vancouver Coastal Health Research Institute

    Vancouver, British Columbia, Canada

  • Sunnybrook Ophthalmology and Vision Services

    Toronto, Ontario, Canada

  • Vitreous Retina Macula Specialists of Toronto

    Toronto, Ontario, Canada

United States
  • Cincinnati Eye Institute

    Cincinnati, Ohio, United States

  • Retina Consultants of Texas

    Bellaire, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
8 Sept 2023
Primary completion
31 Jan 2026
Completion
31 Jan 2030
Last update posted
20 Jan 2026
Registered enrollment
20
Registry id
NCT05984927

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.