Clinical trialNCT06003192RecruitingInterventional

Screen Smart: Using Digital Health to Improve HIV Screening and Prevention

SponsorChildren's Hospital Medical Center, CincinnatiEnrollment63,000HIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this interrupted time series quasi-experimental design study is to implement universal opt- out HIV testing and linkage to HIV preventive care in 15-21 year old adolescents visiting the pediatric emergency department (ED). The main question\[s\] it aims to answer are: 1. What is the uptake, reach and effectiveness of universally offered, opt-out HIV screening across pediatric EDs after implementing an adapted version of a tablet-based screening process? 2. What is the successful linkage to comprehensive HIV pre-exposure prophylaxis (PrEP) care using a novel, digital health platform? Participants will 1. Complete the previously developed and validated computerized sexual health screen (cSHS) containing questions regarding their personal sexual health history 2. Have the opportunity to opt-out of clinician-ordered HIV testing 3. Patients meeting CDC criteria for HIV PrEP will be given the opportunity to enroll in the digital health PrEP linkage platform and followed for 3 months after enrollment.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Jennifer L Reed, MD, MS
Children's Hospital Medical Center, Cincinnati
Principal Investigator
clinicaltrials.gov ↗
Monika Goyal, MD, MSCE
Children's National Research Institute
Principal Investigator
clinicaltrials.gov ↗
Nadia Dowshen, MD, MSHP
Children's Hospital of Philadelphia
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Nationwide Children'S Hospital
Columbus, Ohio, United States
Kristin Stukus, MDMegan Brundrett, MD
Recruiting
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Cynthia Mollen, MD, MSCEMarne Castillo, MEd, PhDSarah Wood, MD, MSCE
Not, yet, recruiting
University of Utah
Salt Lake City, Utah, United States
Not, yet, recruiting
Children'S Wisconsin
Milwaukee, Wisconsin, United States
Claudia Vicetti, MD, MSMichelle Pickett, MD, MS
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 16 Dec 2024
Primary completion: 15 Dec 2027
Completion: 15 Mar 2028
Last update posted: 23 Oct 2026
Registered enrollment: 63,000
Registry id: NCT06003192

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.