Clinical trialNCT06034821Enrolling, by, invitationPhase 4Interventional

Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

SponsorBrigham and Women's HospitalEnrollment1,500Acute Suicidal Depression (ASD)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is a randomized open-label single-blind non-inferiority comparative effectiveness study of ECT vs. KET for the treatment of Acute Suicidal Depression (ASD).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Amit Anand, MD
Brigham and Woman's Hospital, Harvard Medical School
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Center for Addiction and Mental Health (university of Toronto)
Toronto, Ontario, Canada

United States

Uc San Francisco
San Francisco, California, United States
Johns Hopkins University
Baltimore, Maryland, United States
Mclean Hospital
Belmont, Massachusetts, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Mount Sinai School of Medicine
New York, New York, United States
Cleveland Clinic
Cleveland, Ohio, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
Uthealth Houston
Houston, Texas, United States
University of Utah
Salt Lake City, Utah, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Subanesthetic dose intravenous ketamine

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Oct 2023
Primary completion: 1 Oct 2030
Completion: 1 Dec 2030
Last update posted: 15 Dec 2025
Registered enrollment: 1,500
Registry id: NCT06034821

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.